Efectividad, seguridad y aceptabilidad del tratamiento con dimetilfumarato en pacientes con esclerosis múltiple recurrente-remitente en el Hospital Universitario Central de Asturias (Oviedo) que iniciaron tratamiento en 2015
An observational, longitudinal and retrospective study has been carried out with the purpose of evaluate the effectiveness, safety and acceptability of all patients who started the treatment with dimetilfumarato in 2015 at the Hospital Universitario Central de Asturias in Oviedo. The features of the...
| Autores: | , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2018 |
| País: | España |
| Institución: | Universidad de Salamanca (USAL) |
| Repositorio: | GREDOS. Repositorio Institucional de la Universidad de Salamanca |
| OAI Identifier: | oai:gredos.usal.es:10366/136097 |
| Acceso en línea: | http://hdl.handle.net/10366/136097 |
| Access Level: | acceso abierto |
| Palabra clave: | Dimetilfumarato Esclerosis múltiple efectividad seguridad aceptabilidad dimethyl fumarate sclerosis multiple effectiveness safety |
| Sumario: | An observational, longitudinal and retrospective study has been carried out with the purpose of evaluate the effectiveness, safety and acceptability of all patients who started the treatment with dimetilfumarato in 2015 at the Hospital Universitario Central de Asturias in Oviedo. The features of the patients included in the study were similar to those of the pivotal studies (DEFINE and CONFIRM),and in both cases patients were diagnosed with relapsing recurrent multiple sclerosis (RRMS), with a similar range of age and percentages highly close regarding the allocation by sex, being women majority. The study has been carried out during seven months, thus it has not been possible to get solid data of effectivity. It is important to point out that during the period of the study only one patient had a relapse. Regarding safety data it was concluded that most prominent adverse effects were gastrointestinal pain and redness. In order to evaluate the acceptibility of the treatment patients filled a questionaire at the moment when they went to collect the treatment to the Dispensing Area Outpatients. In this regard, we consider that the treatment has been well accepted by patients as it was for oral administration. |
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