Propionate and butyrate counteract renal damage and progression to chronic kidney disease

Short-chain fatty acids (SCFAs), mainly acetate, propionate and butyrate, are produced by gut microbiota through fermentation of complex carbohydrates that cannot be digested by the human host. They affect gut health and can contribute at the distal level to the pathophysiology of several diseases,...

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Bibliographic Details
Authors: Corte-Iglesias, Viviana, Saiz, María L., Andrade-Lopez, Ana Cristina, Salazar, Nuria, Bernet, Cristian Ruiz, Martín-Martín, Cristina, Martínez Borra, Jesús Martinez, Lozano, Juan-Jose, Aransay, Ana M., Díaz-Corte, Carmen, López-Larrea, Carlos, Suárez-Álvarez, Beatriz
Format: article
Status:Published version
Publication Date:2024
Country:España
Institution:Consejo Superior de Investigaciones Científicas (CSIC)
Repository:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/381940
Online Access:http://hdl.handle.net/10261/381940
https://api.elsevier.com/content/abstract/scopus_id/85210573436
Access Level:Open access
Keyword:AKI-to-CKD transition
Acute kidney injury
Fibrosis
Inflammation
Short-chain fatty acids
Description
Summary:Short-chain fatty acids (SCFAs), mainly acetate, propionate and butyrate, are produced by gut microbiota through fermentation of complex carbohydrates that cannot be digested by the human host. They affect gut health and can contribute at the distal level to the pathophysiology of several diseases, including renal pathologies.

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