Propionate and butyrate counteract renal damage and progression to chronic kidney disease

Short-chain fatty acids (SCFAs), mainly acetate, propionate and butyrate, are produced by gut microbiota through fermentation of complex carbohydrates that cannot be digested by the human host. They affect gut health and can contribute at the distal level to the pathophysiology of several diseases,...

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Detalles Bibliográficos
Autores: Corte-Iglesias, Viviana, Saiz, María L., Andrade-Lopez, Ana Cristina, Salazar, Nuria, Bernet, Cristian Ruiz, Martín-Martín, Cristina, Martínez Borra, Jesús Martinez, Lozano, Juan-Jose, Aransay, Ana M., Díaz-Corte, Carmen, López-Larrea, Carlos, Suárez-Álvarez, Beatriz
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/381940
Acceso en línea:http://hdl.handle.net/10261/381940
https://api.elsevier.com/content/abstract/scopus_id/85210573436
Access Level:acceso abierto
Palabra clave:AKI-to-CKD transition
Acute kidney injury
Fibrosis
Inflammation
Short-chain fatty acids
Descripción
Sumario:Short-chain fatty acids (SCFAs), mainly acetate, propionate and butyrate, are produced by gut microbiota through fermentation of complex carbohydrates that cannot be digested by the human host. They affect gut health and can contribute at the distal level to the pathophysiology of several diseases, including renal pathologies.