Analysis of the functional EEG network in an Ecuadorian schizophrenia sample

Background and objectives: Higher mental functions depend on global functional coordination of the brain. Our aim was to study the baseline condition and modulation of functional networks in a previously unevaluated clinical population, compare the results with a population from another country, and...

Descripción completa

Detalles Bibliográficos
Autores: Rodríguez Lorenzana, Alberto, Torres-Tapia, Mabel, Parra, César, Díez, Álvaro, Arjona-Valladares, Antonio, Gómez-Pilar, Javier, Pasquel, Erika, Granizo, Diego, Molina, Vicente
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Universidad Pública de Navarra
Repositorio:Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
OAI Identifier:oai:dnet:academicae__::e7932bc9ebe6ddc245e93b102f97da21
Acceso en línea:https://hdl.handle.net/2454/56875
Access Level:acceso abierto
Palabra clave:Functional network
Graph-theory
Schizophrenia
Electroencephalography
id ES_2a9effbd1632f9cad2a21dffd8dc239e
oai_identifier_str oai:dnet:academicae__::e7932bc9ebe6ddc245e93b102f97da21
network_acronym_str ES
network_name_str España
repository_id_str
spelling Analysis of the functional EEG network in an Ecuadorian schizophrenia sampleRodríguez Lorenzana, AlbertoTorres-Tapia, MabelParra, CésarDíez, ÁlvaroArjona-Valladares, AntonioGómez-Pilar, JavierPasquel, ErikaGranizo, DiegoMolina, VicenteFunctional networkGraph-theorySchizophreniaElectroencephalographyBackground and objectives: Higher mental functions depend on global functional coordination of the brain. Our aim was to study the baseline condition and modulation of functional networks in a previously unevaluated clinical population, compare the results with a population from another country, and analyze their relationship with cognitive functioning. Methods: We evaluated the functioning of brain networks by EEG in 24 patients with schizophrenia and 32 healthy Ecuadorian controls. EEG recordings were made at rest and while performing a P300 task. Small world (SW), Path Length (PL), clustering coefficient (CLC) and connective strength (CS) values were calculated in both conditions. The values obtained were compared between groups, with the results of Spanish patients, and the relationship between the connective parameters and the cognitive performance of the participants was analyzed. Results: Higher PL, CLC and CS values were identified in patients diagnosed with schizophrenia compared to controls (in basal condition) and lower SW values in this same condition. Ecuadorian patients obtained higher values than Spanish patients in the PL and CLC parameters and lower values for the SW parameter, despite these differences, the pattern of alteration in both samples followed the same trend. Finally, the alteration of CS, SW, CLC and PL parameters at baseline was related to cognitive performance.This study is part of a research programme investigating funded by the Universidad de Las Américas.ElsevierCiencias de la SaludOsasun Zientziak2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/mswordhttps://hdl.handle.net/2454/56875reponame:Academica-e. Repositorio Institucional de la Universidad Pública de Navarrainstname:Universidad Pública de NavarraInglés© 2021 The Author(s). Published by Elsevier España, S.L.U. on behalf of Asociación Universitaria de Zaragoza para el Progreso de la Psiquiatría y la Salud Mental. This is an open access article under the CC BY-NC-ND license.https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:dnet:academicae__::e7932bc9ebe6ddc245e93b102f97da212026-06-17T12:41:47Z
dc.title.none.fl_str_mv Analysis of the functional EEG network in an Ecuadorian schizophrenia sample
title Analysis of the functional EEG network in an Ecuadorian schizophrenia sample
spellingShingle Analysis of the functional EEG network in an Ecuadorian schizophrenia sample
Rodríguez Lorenzana, Alberto
Functional network
Graph-theory
Schizophrenia
Electroencephalography
title_short Analysis of the functional EEG network in an Ecuadorian schizophrenia sample
title_full Analysis of the functional EEG network in an Ecuadorian schizophrenia sample
title_fullStr Analysis of the functional EEG network in an Ecuadorian schizophrenia sample
title_full_unstemmed Analysis of the functional EEG network in an Ecuadorian schizophrenia sample
title_sort Analysis of the functional EEG network in an Ecuadorian schizophrenia sample
dc.creator.none.fl_str_mv Rodríguez Lorenzana, Alberto
Torres-Tapia, Mabel
Parra, César
Díez, Álvaro
Arjona-Valladares, Antonio
Gómez-Pilar, Javier
Pasquel, Erika
Granizo, Diego
Molina, Vicente
author Rodríguez Lorenzana, Alberto
author_facet Rodríguez Lorenzana, Alberto
Torres-Tapia, Mabel
Parra, César
Díez, Álvaro
Arjona-Valladares, Antonio
Gómez-Pilar, Javier
Pasquel, Erika
Granizo, Diego
Molina, Vicente
author_role author
author2 Torres-Tapia, Mabel
Parra, César
Díez, Álvaro
Arjona-Valladares, Antonio
Gómez-Pilar, Javier
Pasquel, Erika
Granizo, Diego
Molina, Vicente
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Ciencias de la Salud
Osasun Zientziak
dc.subject.none.fl_str_mv Functional network
Graph-theory
Schizophrenia
Electroencephalography
topic Functional network
Graph-theory
Schizophrenia
Electroencephalography
description Background and objectives: Higher mental functions depend on global functional coordination of the brain. Our aim was to study the baseline condition and modulation of functional networks in a previously unevaluated clinical population, compare the results with a population from another country, and analyze their relationship with cognitive functioning. Methods: We evaluated the functioning of brain networks by EEG in 24 patients with schizophrenia and 32 healthy Ecuadorian controls. EEG recordings were made at rest and while performing a P300 task. Small world (SW), Path Length (PL), clustering coefficient (CLC) and connective strength (CS) values were calculated in both conditions. The values obtained were compared between groups, with the results of Spanish patients, and the relationship between the connective parameters and the cognitive performance of the participants was analyzed. Results: Higher PL, CLC and CS values were identified in patients diagnosed with schizophrenia compared to controls (in basal condition) and lower SW values in this same condition. Ecuadorian patients obtained higher values than Spanish patients in the PL and CLC parameters and lower values for the SW parameter, despite these differences, the pattern of alteration in both samples followed the same trend. Finally, the alteration of CS, SW, CLC and PL parameters at baseline was related to cognitive performance.
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2454/56875
url https://hdl.handle.net/2454/56875
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/msword
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
instname:Universidad Pública de Navarra
instname_str Universidad Pública de Navarra
reponame_str Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
collection Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869405084170846208
score 15.812455

Similares en LA Referencia