Analysis of the functional EEG network in an Ecuadorian schizophrenia sample
Background and objectives: Higher mental functions depend on global functional coordination of the brain. Our aim was to study the baseline condition and modulation of functional networks in a previously unevaluated clinical population, compare the results with a population from another country, and...
| Autores: | , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Universidad Pública de Navarra |
| Repositorio: | Academica-e. Repositorio Institucional de la Universidad Pública de Navarra |
| OAI Identifier: | oai:dnet:academicae__::e7932bc9ebe6ddc245e93b102f97da21 |
| Acceso en línea: | https://hdl.handle.net/2454/56875 |
| Access Level: | acceso abierto |
| Palabra clave: | Functional network Graph-theory Schizophrenia Electroencephalography |
| Sumario: | Background and objectives: Higher mental functions depend on global functional coordination of the brain. Our aim was to study the baseline condition and modulation of functional networks in a previously unevaluated clinical population, compare the results with a population from another country, and analyze their relationship with cognitive functioning. Methods: We evaluated the functioning of brain networks by EEG in 24 patients with schizophrenia and 32 healthy Ecuadorian controls. EEG recordings were made at rest and while performing a P300 task. Small world (SW), Path Length (PL), clustering coefficient (CLC) and connective strength (CS) values were calculated in both conditions. The values obtained were compared between groups, with the results of Spanish patients, and the relationship between the connective parameters and the cognitive performance of the participants was analyzed. Results: Higher PL, CLC and CS values were identified in patients diagnosed with schizophrenia compared to controls (in basal condition) and lower SW values in this same condition. Ecuadorian patients obtained higher values than Spanish patients in the PL and CLC parameters and lower values for the SW parameter, despite these differences, the pattern of alteration in both samples followed the same trend. Finally, the alteration of CS, SW, CLC and PL parameters at baseline was related to cognitive performance. |
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