Nanostructured medical sutures with antibacterial properties

Bacterial repellence in suture materials is a desirable property that can potentially improve the healing process by preventing infection. We describe a method for generating nanostructures at the surface of commercial sutures of different composition, and their potential for preventing biofilm form...

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Detalles Bibliográficos
Autores: Serrano, Cristina, García-Fernández, Luis, Fernandez-Blazquez, juan Pedro, Barbeck, Mike, Ghanaati, Shahram, Unger, Ron, Kirkpatrick, James, Arzt, Eduard, Funk, Lutz, Turon, Pau, Campo, Aranzazu del
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2015
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/378056
Acceso en línea:http://hdl.handle.net/10261/378056
Access Level:acceso abierto
Palabra clave:Nanopatterning
Antifouling
Antibacterial
Plasma treatment
Sutures
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spelling Nanostructured medical sutures with antibacterial propertiesSerrano, CristinaGarcía-Fernández, LuisFernandez-Blazquez, juan PedroBarbeck, MikeGhanaati, ShahramUnger, RonKirkpatrick, JamesArzt, EduardFunk, LutzTuron, PauCampo, Aranzazu delNanopatterningAntifoulingAntibacterialPlasma treatmentSuturesBacterial repellence in suture materials is a desirable property that can potentially improve the healing process by preventing infection. We describe a method for generating nanostructures at the surface of commercial sutures of different composition, and their potential for preventing biofilm formation. We show how bacteria attachment is altered in the presence of nanosized topographies and identify optimum designs for preventing it without compromising biocompatibility and applicability in terms of nanostructure robustness or tissue friction. These studies open new possibilities for flexible and cost-effective realization of topography-based antibacterial coatings for absorbable biomedical textiles.Authors acknowledge financial support from BMBF (FixNaht, FKZ 13EZ1105) and thank Dr. Rüdiger Berger (MPI-P, Mainz) for AFM measurements.Peer reviewedElsevier202520252015info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Postprintinfo:eu-repo/semantics/acceptedVersionhttp://hdl.handle.net/10261/378056reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttp://dx.doi.org/10.1016/j.biomaterials.2015.02.039Noinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3780562026-05-22T06:33:51Z
dc.title.none.fl_str_mv Nanostructured medical sutures with antibacterial properties
title Nanostructured medical sutures with antibacterial properties
spellingShingle Nanostructured medical sutures with antibacterial properties
Serrano, Cristina
Nanopatterning
Antifouling
Antibacterial
Plasma treatment
Sutures
title_short Nanostructured medical sutures with antibacterial properties
title_full Nanostructured medical sutures with antibacterial properties
title_fullStr Nanostructured medical sutures with antibacterial properties
title_full_unstemmed Nanostructured medical sutures with antibacterial properties
title_sort Nanostructured medical sutures with antibacterial properties
dc.creator.none.fl_str_mv Serrano, Cristina
García-Fernández, Luis
Fernandez-Blazquez, juan Pedro
Barbeck, Mike
Ghanaati, Shahram
Unger, Ron
Kirkpatrick, James
Arzt, Eduard
Funk, Lutz
Turon, Pau
Campo, Aranzazu del
author Serrano, Cristina
author_facet Serrano, Cristina
García-Fernández, Luis
Fernandez-Blazquez, juan Pedro
Barbeck, Mike
Ghanaati, Shahram
Unger, Ron
Kirkpatrick, James
Arzt, Eduard
Funk, Lutz
Turon, Pau
Campo, Aranzazu del
author_role author
author2 García-Fernández, Luis
Fernandez-Blazquez, juan Pedro
Barbeck, Mike
Ghanaati, Shahram
Unger, Ron
Kirkpatrick, James
Arzt, Eduard
Funk, Lutz
Turon, Pau
Campo, Aranzazu del
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Nanopatterning
Antifouling
Antibacterial
Plasma treatment
Sutures
topic Nanopatterning
Antifouling
Antibacterial
Plasma treatment
Sutures
description Bacterial repellence in suture materials is a desirable property that can potentially improve the healing process by preventing infection. We describe a method for generating nanostructures at the surface of commercial sutures of different composition, and their potential for preventing biofilm formation. We show how bacteria attachment is altered in the presence of nanosized topographies and identify optimum designs for preventing it without compromising biocompatibility and applicability in terms of nanostructure robustness or tissue friction. These studies open new possibilities for flexible and cost-effective realization of topography-based antibacterial coatings for absorbable biomedical textiles.
publishDate 2015
dc.date.none.fl_str_mv 2015
2025
2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Postprint
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/378056
url http://hdl.handle.net/10261/378056
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv http://dx.doi.org/10.1016/j.biomaterials.2015.02.039
No
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.812429

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