Nanostructured medical sutures with antibacterial properties

Bacterial repellence in suture materials is a desirable property that can potentially improve the healing process by preventing infection. We describe a method for generating nanostructures at the surface of commercial sutures of different composition, and their potential for preventing biofilm form...

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Detalles Bibliográficos
Autores: Serrano, Cristina, García-Fernández, Luis, Fernandez-Blazquez, juan Pedro, Barbeck, Mike, Ghanaati, Shahram, Unger, Ron, Kirkpatrick, James, Arzt, Eduard, Funk, Lutz, Turon, Pau, Campo, Aranzazu del
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2015
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/378056
Acceso en línea:http://hdl.handle.net/10261/378056
Access Level:acceso abierto
Palabra clave:Nanopatterning
Antifouling
Antibacterial
Plasma treatment
Sutures
Descripción
Sumario:Bacterial repellence in suture materials is a desirable property that can potentially improve the healing process by preventing infection. We describe a method for generating nanostructures at the surface of commercial sutures of different composition, and their potential for preventing biofilm formation. We show how bacteria attachment is altered in the presence of nanosized topographies and identify optimum designs for preventing it without compromising biocompatibility and applicability in terms of nanostructure robustness or tissue friction. These studies open new possibilities for flexible and cost-effective realization of topography-based antibacterial coatings for absorbable biomedical textiles.