The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case–control study, Spain, 2013/14 and 2014/15

Influenza vaccination may limit the impact of influenza in the community. The aim of this study was to assess the effectiveness of influenza vaccination in preventing hospitalisation in individuals aged ≥ 65 years in Spain. A multicentre case–control study was conducted in 20 Spanish hospitals durin...

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Autores: Domínguez García, Àngela, Soldevila, Núria, Toledo, Diana, Godoy i García, Pere, Espejo, Elena, Fernandez, Maria Amelia, Mayoral, José María, Castilla, Jesús, Egurrola, Mikel, Tamames, Sonia, Astray, Jenaro, Morales, María
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Institución:Universitat de Lleida (UdL)
Repositorio:Repositori Obert UdL
OAI Identifier:oai:repositori.udl.cat:10459.1/60322
Acceso en línea:https://doi.org/10.2807/1560-7917.ES.2017.22.34.30602
http://hdl.handle.net/10459.1/60322
Access Level:acceso abierto
Palabra clave:Preventing hospitalisations
Elderly individuals
Spain
Influenza vaccination
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spelling The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case–control study, Spain, 2013/14 and 2014/15Domínguez García, ÀngelaSoldevila, NúriaToledo, DianaGodoy i García, PereEspejo, ElenaFernandez, Maria AmeliaMayoral, José MaríaCastilla, JesúsEgurrola, MikelTamames, SoniaAstray, JenaroMorales, MaríaPreventing hospitalisationsElderly individualsSpainInfluenza vaccinationInfluenza vaccination may limit the impact of influenza in the community. The aim of this study was to assess the effectiveness of influenza vaccination in preventing hospitalisation in individuals aged ≥ 65 years in Spain. A multicentre case–control study was conducted in 20 Spanish hospitals during 2013/14 and 2014/15. Patients aged ≥ 65 years who were hospitalised with laboratory-confirmed influenza were matched with controls according to sex, age and date of hospitalisation. Adjusted vaccine effectiveness (VE) was calculated by multivariate conditional logistic regression. A total of 728 cases and 1,826 matched controls were included in the study. Overall VE was 36% (95% confidence interval (CI): 22–47). VE was 51% (95% CI: 15–71) in patients without high-risk medical conditions and 30% (95% CI: 14–44) in patients with them. VE was 39% (95% CI: 20–53) in patients aged 65–79 years and 34% (95% CI: 11–51) in patients aged ≥ 80 years, and was greater against the influenza A(H1N1)pdm09 subtype than the A(H3N2) subtype. Influenza vaccination was effective in preventing hospitalisations of elderly individuals.This work was supported by the National Plan of I+D+I 2008–2011 and ISCIII-Subdirección General de Evaluación y Fomento de la Investigación (Project PI12/02079), and cofunded by Fondo Europeo de Desarrollo Regional (FEDER) and the Catalan Agency for the Management of Grants for University Research (AGAUR grant number 2014/ SGR 1403).European Centre for Disease Prevention and Control2017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://doi.org/10.2807/1560-7917.ES.2017.22.34.30602http://hdl.handle.net/10459.1/60322reponame:Repositori Obert UdL instname:Universitat de Lleida (UdL)InglésReproducció del document publicat a https://doi.org/10.2807/1560-7917.ES.2017.22.34.30602Eurosurveillance, 2017, vol. 22, núm. 34, p. 1-8cc-by (c) Domínguez et al., 2017info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/oai:repositori.udl.cat:10459.1/603222026-06-24T12:42:17Z
dc.title.none.fl_str_mv The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case–control study, Spain, 2013/14 and 2014/15
title The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case–control study, Spain, 2013/14 and 2014/15
spellingShingle The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case–control study, Spain, 2013/14 and 2014/15
Domínguez García, Àngela
Preventing hospitalisations
Elderly individuals
Spain
Influenza vaccination
title_short The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case–control study, Spain, 2013/14 and 2014/15
title_full The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case–control study, Spain, 2013/14 and 2014/15
title_fullStr The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case–control study, Spain, 2013/14 and 2014/15
title_full_unstemmed The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case–control study, Spain, 2013/14 and 2014/15
title_sort The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case–control study, Spain, 2013/14 and 2014/15
dc.creator.none.fl_str_mv Domínguez García, Àngela
Soldevila, Núria
Toledo, Diana
Godoy i García, Pere
Espejo, Elena
Fernandez, Maria Amelia
Mayoral, José María
Castilla, Jesús
Egurrola, Mikel
Tamames, Sonia
Astray, Jenaro
Morales, María
author Domínguez García, Àngela
author_facet Domínguez García, Àngela
Soldevila, Núria
Toledo, Diana
Godoy i García, Pere
Espejo, Elena
Fernandez, Maria Amelia
Mayoral, José María
Castilla, Jesús
Egurrola, Mikel
Tamames, Sonia
Astray, Jenaro
Morales, María
author_role author
author2 Soldevila, Núria
Toledo, Diana
Godoy i García, Pere
Espejo, Elena
Fernandez, Maria Amelia
Mayoral, José María
Castilla, Jesús
Egurrola, Mikel
Tamames, Sonia
Astray, Jenaro
Morales, María
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Preventing hospitalisations
Elderly individuals
Spain
Influenza vaccination
topic Preventing hospitalisations
Elderly individuals
Spain
Influenza vaccination
description Influenza vaccination may limit the impact of influenza in the community. The aim of this study was to assess the effectiveness of influenza vaccination in preventing hospitalisation in individuals aged ≥ 65 years in Spain. A multicentre case–control study was conducted in 20 Spanish hospitals during 2013/14 and 2014/15. Patients aged ≥ 65 years who were hospitalised with laboratory-confirmed influenza were matched with controls according to sex, age and date of hospitalisation. Adjusted vaccine effectiveness (VE) was calculated by multivariate conditional logistic regression. A total of 728 cases and 1,826 matched controls were included in the study. Overall VE was 36% (95% confidence interval (CI): 22–47). VE was 51% (95% CI: 15–71) in patients without high-risk medical conditions and 30% (95% CI: 14–44) in patients with them. VE was 39% (95% CI: 20–53) in patients aged 65–79 years and 34% (95% CI: 11–51) in patients aged ≥ 80 years, and was greater against the influenza A(H1N1)pdm09 subtype than the A(H3N2) subtype. Influenza vaccination was effective in preventing hospitalisations of elderly individuals.
publishDate 2017
dc.date.none.fl_str_mv 2017
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.2807/1560-7917.ES.2017.22.34.30602
http://hdl.handle.net/10459.1/60322
url https://doi.org/10.2807/1560-7917.ES.2017.22.34.30602
http://hdl.handle.net/10459.1/60322
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a https://doi.org/10.2807/1560-7917.ES.2017.22.34.30602
Eurosurveillance, 2017, vol. 22, núm. 34, p. 1-8
dc.rights.none.fl_str_mv cc-by (c) Domínguez et al., 2017
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
rights_invalid_str_mv cc-by (c) Domínguez et al., 2017
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv European Centre for Disease Prevention and Control
publisher.none.fl_str_mv European Centre for Disease Prevention and Control
dc.source.none.fl_str_mv reponame:Repositori Obert UdL
instname:Universitat de Lleida (UdL)
instname_str Universitat de Lleida (UdL)
reponame_str Repositori Obert UdL
collection Repositori Obert UdL
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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