The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: A multicentre case–control study, Spain, 2013/14 and 2014/15

[EN] Influenza vaccination may limit the impact of influenza in the community. The aim of this study was to assess the effectiveness of influenza vaccination in preventing hospitalisation in individuals aged ≥ 65 years in Spain. A multicentre case–control study was conducted in 20 Spanish hospitals...

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Detalles Bibliográficos
Autores: Suárez, Ángela, Soldevilla, Nuria, Toledo, Diana, Godoy, Pere, Espejo, Elena, Fernández, Maria Amelia, Mayoral, José María, Castilla, Jesús, Egurrola, Mikel, Tamanes, Sonia, Astray, Jenaro, Suárez Varela, María Morales, Fernández Villa, Tania, Martín Sánchez, Vicente
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Institución:Universidad de León
Repositorio:BULERIA. Repositorio Institucional de la Universidad de León
OAI Identifier:oai:buleria.unileon.es:10612/22361
Acceso en línea:https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2017.22.34.30602
https://hdl.handle.net/10612/22361
Access Level:acceso abierto
Palabra clave:Medicina. Salud
Vaccination
Descripción
Sumario:[EN] Influenza vaccination may limit the impact of influenza in the community. The aim of this study was to assess the effectiveness of influenza vaccination in preventing hospitalisation in individuals aged ≥ 65 years in Spain. A multicentre case–control study was conducted in 20 Spanish hospitals during 2013/14 and 2014/15. Patients aged ≥ 65 years who were hospitalised with laboratory-confirmed influenza were matched with controls according to sex, age and date of hospitalisation. Adjusted vaccine effectiveness (VE) was calculated by multivariate conditional logistic regression. A total of 728 cases and 1,826 matched controls were included in the study. Overall VE was 36% (95% confidence interval (CI): 22–47). VE was 51% (95% CI: 15–71) in patients without high-risk medical conditions and 30% (95% CI: 14–44) in patients with them. VE was 39% (95% CI: 20–53) in patients aged 65–79 years and 34% (95% CI: 11–51) in patients aged ≥ 80 years, and was greater against the influenza A(H1N1)pdm09 subtype than the A(H3N2) subtype. Influenza vaccination was effective in preventing hospitalisations of elderly individuals.

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