Stimuli-responsive control of cyclic peptide nanotubes towards biological applications

The dynamic behaviour of supramolecular systems has facilitated the incorporation of stimuli-responsive capabilities into these materials, thereby broadening their range of applications. In this context, self-assembling cyclic peptide nanotubes emerge as a promising alternative for the construction...

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Detalles Bibliográficos
Autor: Vilela Picos, Marcos
Tipo de recurso: tesis doctoral
Fecha de publicación:2025
País:España
Institución:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/40962
Acceso en línea:https://hdl.handle.net/10347/40962
Access Level:acceso abierto
Palabra clave:cyclic peptides
nanotubes
self-assembly
stimuli-responsive
drug delivery
230224 Péptidos
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spelling Stimuli-responsive control of cyclic peptide nanotubes towards biological applicationsVilela Picos, Marcoscyclic peptidesnanotubesself-assemblystimuli-responsivedrug delivery230224 PéptidosThe dynamic behaviour of supramolecular systems has facilitated the incorporation of stimuli-responsive capabilities into these materials, thereby broadening their range of applications. In this context, self-assembling cyclic peptide nanotubes emerge as a promising alternative for the construction of this type of systems. These tubular assemblies are formed by the controlled stacking of cyclic peptide units with a flat conformation through hydrogen bonding interactions. This doctoral thesis proposes different strategies for obtaining stimuli-responsive cyclic peptide nanotubes in order to control their self-assembly process or to develop drug delivery applications. The results represent an initial step towards future new self-assembly properties and biological applications for cyclic peptide nanotubes.Granja Guillán, Juan RamónAmorín López, ManuelUniversidade de Santiago de Compostela. Escola de Doutoramento Internacional (EDIUS)20252025-01-0120252025-01-01doctoral thesishttp://purl.org/coar/resource_type/c_db06info:eu-repo/semantics/doctoralThesisapplication/pdfhttps://hdl.handle.net/10347/40962reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostelainstname:Universidad de Santiago de Compostela (USC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:minerva.usc.gal:10347/409622026-06-15T12:47:27Z
dc.title.none.fl_str_mv Stimuli-responsive control of cyclic peptide nanotubes towards biological applications
title Stimuli-responsive control of cyclic peptide nanotubes towards biological applications
spellingShingle Stimuli-responsive control of cyclic peptide nanotubes towards biological applications
Vilela Picos, Marcos
cyclic peptides
nanotubes
self-assembly
stimuli-responsive
drug delivery
230224 Péptidos
title_short Stimuli-responsive control of cyclic peptide nanotubes towards biological applications
title_full Stimuli-responsive control of cyclic peptide nanotubes towards biological applications
title_fullStr Stimuli-responsive control of cyclic peptide nanotubes towards biological applications
title_full_unstemmed Stimuli-responsive control of cyclic peptide nanotubes towards biological applications
title_sort Stimuli-responsive control of cyclic peptide nanotubes towards biological applications
dc.creator.none.fl_str_mv Vilela Picos, Marcos
author Vilela Picos, Marcos
author_facet Vilela Picos, Marcos
author_role author
dc.contributor.none.fl_str_mv Granja Guillán, Juan Ramón
Amorín López, Manuel
Universidade de Santiago de Compostela. Escola de Doutoramento Internacional (EDIUS)
dc.subject.none.fl_str_mv cyclic peptides
nanotubes
self-assembly
stimuli-responsive
drug delivery
230224 Péptidos
topic cyclic peptides
nanotubes
self-assembly
stimuli-responsive
drug delivery
230224 Péptidos
description The dynamic behaviour of supramolecular systems has facilitated the incorporation of stimuli-responsive capabilities into these materials, thereby broadening their range of applications. In this context, self-assembling cyclic peptide nanotubes emerge as a promising alternative for the construction of this type of systems. These tubular assemblies are formed by the controlled stacking of cyclic peptide units with a flat conformation through hydrogen bonding interactions. This doctoral thesis proposes different strategies for obtaining stimuli-responsive cyclic peptide nanotubes in order to control their self-assembly process or to develop drug delivery applications. The results represent an initial step towards future new self-assembly properties and biological applications for cyclic peptide nanotubes.
publishDate 2025
dc.date.none.fl_str_mv 2025
2025-01-01
2025
2025-01-01
dc.type.none.fl_str_mv doctoral thesis
http://purl.org/coar/resource_type/c_db06
dc.type.openaire.fl_str_mv info:eu-repo/semantics/doctoralThesis
format doctoralThesis
dc.identifier.none.fl_str_mv https://hdl.handle.net/10347/40962
url https://hdl.handle.net/10347/40962
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname:Universidad de Santiago de Compostela (USC)
instname_str Universidad de Santiago de Compostela (USC)
reponame_str Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
collection Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
repository.name.fl_str_mv
repository.mail.fl_str_mv
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