Stimuli-responsive control of cyclic peptide nanotubes towards biological applications
The dynamic behaviour of supramolecular systems has facilitated the incorporation of stimuli-responsive capabilities into these materials, thereby broadening their range of applications. In this context, self-assembling cyclic peptide nanotubes emerge as a promising alternative for the construction...
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| Tipo de recurso: | tesis doctoral |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Universidad de Santiago de Compostela (USC) |
| Repositorio: | Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela |
| Idioma: | inglés |
| OAI Identifier: | oai:minerva.usc.gal:10347/40962 |
| Acceso en línea: | https://hdl.handle.net/10347/40962 |
| Access Level: | acceso abierto |
| Palabra clave: | cyclic peptides nanotubes self-assembly stimuli-responsive drug delivery 230224 Péptidos |
| Sumario: | The dynamic behaviour of supramolecular systems has facilitated the incorporation of stimuli-responsive capabilities into these materials, thereby broadening their range of applications. In this context, self-assembling cyclic peptide nanotubes emerge as a promising alternative for the construction of this type of systems. These tubular assemblies are formed by the controlled stacking of cyclic peptide units with a flat conformation through hydrogen bonding interactions. This doctoral thesis proposes different strategies for obtaining stimuli-responsive cyclic peptide nanotubes in order to control their self-assembly process or to develop drug delivery applications. The results represent an initial step towards future new self-assembly properties and biological applications for cyclic peptide nanotubes. |
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