Relationship between rheumatoid arthritis and interstitial lung disease is a ‘two-way street’. Response to: ‘Autoantibodies and interstitial lung disease in rheumatoid arthritis: towards a ‘mix-and-match’ approach’ by Alunno et al
We welcome the comments by Alunno et al. on our article about the association between anti-carbamylated protein antibody (Anti-CarP) specificities and rheumatoid arthritis-associated interstitial lung disease (RA-ILD) (1). The authors proposed a “mix and match approach” consisting of the assessment...
| Autores: | , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión aceptada para publicación |
| Fecha de publicación: | 2020 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/216627 |
| Acceso en línea: | http://hdl.handle.net/10261/216627 |
| Access Level: | acceso abierto |
| Palabra clave: | Anti-CarP ACPA Autoantibodies Rheumatoid arthritis Pulmonary fibrosis |
| Sumario: | We welcome the comments by Alunno et al. on our article about the association between anti-carbamylated protein antibody (Anti-CarP) specificities and rheumatoid arthritis-associated interstitial lung disease (RA-ILD) (1). The authors proposed a “mix and match approach” consisting of the assessment of various antibody specificities at RA diagnosis with the aim of predicting the development of ILD (2). We believe this hypothesis is reasonable, considering that different anti-modified protein antibodies (AMPA) including Anti-CarP, anti-citrullinated and anti-acetylated protein antibodies (ACPA and anti-AceP, respectively) have been associated with RA-ILD (1, 3, 4). Furthermore, a greater number of coexisting specificities of a single AMPA have been found in RA-ILD patients (3, 5). |
|---|