Anti-carbamylated protein antibody isotype pattern differs between palindromic rheumatism and rheumatoid arthritis

[Background]: A restricted response against citrullinated peptides/proteins, with less isotype usage, has been found in palindromic rheumatism (PR) in comparison with rheumatoid arthritis (RA). We hypothesized that this different antibody response may be observed for other post-translational modifie...

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Detalles Bibliográficos
Autores: Castellanos-Moreira, Raul, Rodriguez-García, Sebastian C., Cabrero-Villalba, Sonia, Gómara Elena, María José, Salvador, Georgina, Ruiz-Esquide, Virginia, Ramírez, Julio, Inciarte-Mundo, José, Morlà, Rosa, García-Moreno, Cristina, Cuervo, Andrea, Gómez-Puerta, José A., Cañete, Juan D., Haro Villar, Isabel, Sanmartí, Raimon
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/226112
Acceso en línea:http://hdl.handle.net/10261/226112
Access Level:acceso abierto
Palabra clave:ACPA
Anti-CarP
B cells
Autoantibodies
Palindromic rheumatism
Rheumatoid arthritis
Descripción
Sumario:[Background]: A restricted response against citrullinated peptides/proteins, with less isotype usage, has been found in palindromic rheumatism (PR) in comparison with rheumatoid arthritis (RA). We hypothesized that this different antibody response may be observed for other post-translational modified proteins. We compared the prevalence and isotype usage of two specificities of anti-carbamylated peptide/protein antibodies (Anti-CarP) in patients with PR and RA.

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