Amino-acid-based surfactants: New antimicrobial agents

The rapid increase of drug resistant bacteria makes necessary the development of new antimicrobial agents. Synthetic amino acid-based surfactants constitute a promising alternative to conventional antimicrobial compounds given that they can be prepared from renewable raw materials. In this review, w...

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Detalles Bibliográficos
Autores: Pinazo Gassol, Aurora, Manresa Presas, Ma. Ángeles (María Ángeles), Marqués Villavecchia, Ana M., Bustelo, M., Espuny Tomás, Ma. José (María José), Pérez Muñoz, Lourdes
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2016
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/132741
Acceso en línea:https://hdl.handle.net/2445/132741
Access Level:acceso abierto
Palabra clave:Agents tensioactius
Tecnologia farmacèutica
Fórmules magistrals
Agents antiinfecciosos
Microbiologia
Aminoàcids
Toxicitat dels medicaments
Surface active agents
Pharmaceutical technology
Medical formularies
Anti-infective agents
Microbiology
Amino acids
Drug toxicity
Descripción
Sumario:The rapid increase of drug resistant bacteria makes necessary the development of new antimicrobial agents. Synthetic amino acid-based surfactants constitute a promising alternative to conventional antimicrobial compounds given that they can be prepared from renewable raw materials. In this review, we discuss the structural features that promote antimicrobial activity of amino acid-based surfactants. Monocatenary, dicatenary and gemini surfactants that contain different amino acids on the polar head and show activity against bacteria are revised. The synthesis and basic physico-chemical properties have also been included.