Comparing Infection Profiles of Expectant Mothers with COVID-19 and Impacts on Maternal and Perinatal Outcomes between the First Two Waves of the Pandemic

During 2020, Coronavirus Disease-19 (COVID-19) incidence fluctuated in two clear waves across the spring and autumn periods. This study was designed to compare the maternal and perinatal clinical outcomes in obstetrics patients with COVID-19 between the two waves of infection in Spain. We conducted...

Descripción completa

Detalles Bibliográficos
Autores: Cuñarro López, Yolanda, Hernández Martín, Concepción, Pintado Recarte, María Del Pilar, Payá Martínez, Pilar, López Pérez, Rocío, Cueto Hernández, Ignacio, Ruiz Labarta, Javier, Cano Valderrama, Óscar, Martínez Pérez, Óscar, Bravo Arribas, Coral, Ortega, Miguel A., De León Luis, Juan Antonio
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/7412
Acceso en línea:https://hdl.handle.net/20.500.14352/7412
Access Level:acceso abierto
Palabra clave:618.2
616.9
COVID-19
Pregnancy
Maternal and perinatal medicine
Morbidity
Medicina
Enfermedades infecciosas
Ginecología y obstetricia
32 Ciencias Médicas
3205.05 Enfermedades Infecciosas
3201.08 Ginecología
id ES_285ffb68f1115dff4ed6f97fa668c56e
oai_identifier_str oai:docta.ucm.es:20.500.14352/7412
network_acronym_str ES
network_name_str España
repository_id_str
spelling Comparing Infection Profiles of Expectant Mothers with COVID-19 and Impacts on Maternal and Perinatal Outcomes between the First Two Waves of the PandemicCuñarro López, YolandaHernández Martín, ConcepciónPintado Recarte, María Del PilarPayá Martínez, PilarLópez Pérez, RocíoCueto Hernández, IgnacioRuiz Labarta, JavierCano Valderrama, ÓscarMartínez Pérez, ÓscarBravo Arribas, CoralOrtega, Miguel A.De León Luis, Juan Antonio618.2616.9COVID-19PregnancyMaternal and perinatal medicineMorbidityMedicinaEnfermedades infecciosasGinecología y obstetricia32 Ciencias Médicas3205.05 Enfermedades Infecciosas3201.08 GinecologíaDuring 2020, Coronavirus Disease-19 (COVID-19) incidence fluctuated in two clear waves across the spring and autumn periods. This study was designed to compare the maternal and perinatal clinical outcomes in obstetrics patients with COVID-19 between the two waves of infection in Spain. We conducted an observational, analytical, ambispective cohort study with longitudinal follow-up of mothers with confirmed SARV-CoV-2 infection from different hospitals in our country between March–November 2020. We recruited 1295 pregnant women with SARS-CoV2 infection from 78 hospitals, 846 (65.3%) of whom were diagnosed during the first wave and 449 (34.7%) during the second wave. Our results show that patients developing COVID-19 during the first wave had more symptoms at triage, early in pregnancy with greater rates of COVID-19-related maternal morbidity; caesarean section and preterm birth in the first wave. We register two cases of maternal mortality and only during the first wave. Maternal morbidity events showed a strong link to perinatal mortality events in the first wave compared to the second wave, in which maternal morbidity was more associated with pneumonia. Likewise, maternal morbidity showed a strong correlation with perinatal morbidity events in both waves. We describe the differences between the patients’ profiles and management between the two waves and related to maternal and perinatal outcomes. Differences were also observed in the management of pregnant women with COVID-19. Thus, there were fewer caesarean sections, and maternal and perinatal morbidity events were reduced in the second wave, while the impacts of respiratory symptoms and their severity, including a greater need for maternal treatment, were greater in this last period. Identifying the impact that changes in the profile as well as in the treatment have on maternal–perinatal morbidity and mortality will help improve the well-being of our patients and their newborns.MDPIUniversidad Complutense de Madrid20212021-06-2520212021-06-25journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/7412reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Atribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/74122026-06-02T12:44:21Z
dc.title.none.fl_str_mv Comparing Infection Profiles of Expectant Mothers with COVID-19 and Impacts on Maternal and Perinatal Outcomes between the First Two Waves of the Pandemic
title Comparing Infection Profiles of Expectant Mothers with COVID-19 and Impacts on Maternal and Perinatal Outcomes between the First Two Waves of the Pandemic
spellingShingle Comparing Infection Profiles of Expectant Mothers with COVID-19 and Impacts on Maternal and Perinatal Outcomes between the First Two Waves of the Pandemic
Cuñarro López, Yolanda
618.2
616.9
COVID-19
Pregnancy
Maternal and perinatal medicine
Morbidity
Medicina
Enfermedades infecciosas
Ginecología y obstetricia
32 Ciencias Médicas
3205.05 Enfermedades Infecciosas
3201.08 Ginecología
title_short Comparing Infection Profiles of Expectant Mothers with COVID-19 and Impacts on Maternal and Perinatal Outcomes between the First Two Waves of the Pandemic
title_full Comparing Infection Profiles of Expectant Mothers with COVID-19 and Impacts on Maternal and Perinatal Outcomes between the First Two Waves of the Pandemic
title_fullStr Comparing Infection Profiles of Expectant Mothers with COVID-19 and Impacts on Maternal and Perinatal Outcomes between the First Two Waves of the Pandemic
title_full_unstemmed Comparing Infection Profiles of Expectant Mothers with COVID-19 and Impacts on Maternal and Perinatal Outcomes between the First Two Waves of the Pandemic
title_sort Comparing Infection Profiles of Expectant Mothers with COVID-19 and Impacts on Maternal and Perinatal Outcomes between the First Two Waves of the Pandemic
dc.creator.none.fl_str_mv Cuñarro López, Yolanda
Hernández Martín, Concepción
Pintado Recarte, María Del Pilar
Payá Martínez, Pilar
López Pérez, Rocío
Cueto Hernández, Ignacio
Ruiz Labarta, Javier
Cano Valderrama, Óscar
Martínez Pérez, Óscar
Bravo Arribas, Coral
Ortega, Miguel A.
De León Luis, Juan Antonio
author Cuñarro López, Yolanda
author_facet Cuñarro López, Yolanda
Hernández Martín, Concepción
Pintado Recarte, María Del Pilar
Payá Martínez, Pilar
López Pérez, Rocío
Cueto Hernández, Ignacio
Ruiz Labarta, Javier
Cano Valderrama, Óscar
Martínez Pérez, Óscar
Bravo Arribas, Coral
Ortega, Miguel A.
De León Luis, Juan Antonio
author_role author
author2 Hernández Martín, Concepción
Pintado Recarte, María Del Pilar
Payá Martínez, Pilar
López Pérez, Rocío
Cueto Hernández, Ignacio
Ruiz Labarta, Javier
Cano Valderrama, Óscar
Martínez Pérez, Óscar
Bravo Arribas, Coral
Ortega, Miguel A.
De León Luis, Juan Antonio
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidad Complutense de Madrid
dc.subject.none.fl_str_mv 618.2
616.9
COVID-19
Pregnancy
Maternal and perinatal medicine
Morbidity
Medicina
Enfermedades infecciosas
Ginecología y obstetricia
32 Ciencias Médicas
3205.05 Enfermedades Infecciosas
3201.08 Ginecología
topic 618.2
616.9
COVID-19
Pregnancy
Maternal and perinatal medicine
Morbidity
Medicina
Enfermedades infecciosas
Ginecología y obstetricia
32 Ciencias Médicas
3205.05 Enfermedades Infecciosas
3201.08 Ginecología
description During 2020, Coronavirus Disease-19 (COVID-19) incidence fluctuated in two clear waves across the spring and autumn periods. This study was designed to compare the maternal and perinatal clinical outcomes in obstetrics patients with COVID-19 between the two waves of infection in Spain. We conducted an observational, analytical, ambispective cohort study with longitudinal follow-up of mothers with confirmed SARV-CoV-2 infection from different hospitals in our country between March–November 2020. We recruited 1295 pregnant women with SARS-CoV2 infection from 78 hospitals, 846 (65.3%) of whom were diagnosed during the first wave and 449 (34.7%) during the second wave. Our results show that patients developing COVID-19 during the first wave had more symptoms at triage, early in pregnancy with greater rates of COVID-19-related maternal morbidity; caesarean section and preterm birth in the first wave. We register two cases of maternal mortality and only during the first wave. Maternal morbidity events showed a strong link to perinatal mortality events in the first wave compared to the second wave, in which maternal morbidity was more associated with pneumonia. Likewise, maternal morbidity showed a strong correlation with perinatal morbidity events in both waves. We describe the differences between the patients’ profiles and management between the two waves and related to maternal and perinatal outcomes. Differences were also observed in the management of pregnant women with COVID-19. Thus, there were fewer caesarean sections, and maternal and perinatal morbidity events were reduced in the second wave, while the impacts of respiratory symptoms and their severity, including a greater need for maternal treatment, were greater in this last period. Identifying the impact that changes in the profile as well as in the treatment have on maternal–perinatal morbidity and mortality will help improve the well-being of our patients and their newborns.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-06-25
2021
2021-06-25
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/7412
url https://hdl.handle.net/20.500.14352/7412
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 3.0 España
https://creativecommons.org/licenses/by/3.0/es/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 3.0 España
https://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869404942432731136
score 15,300719

Similares en LA Referencia