The Profile of the Obstetric Patients with SARS-CoV-2 Infection According to Country of Origin of the Publication: A Systematic Review of the Literature

SARS-CoV-2 is the novel member of coronavirus responsible for the worldwide pandemic COVID-19, affecting all types of people. In this context, established research identified pregnant women as a susceptible group of SARS-CoV-2 infection, although there is still limited data regarding the real impact...

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Detalles Bibliográficos
Autores: Cuñarro López, Yolanda, Pintado Recarte, María Del Pilar, Cueto Hernández, Ignacio, Hernández Martín, Concepción, Payá Martínez, María Pilar, Muñóz Chápuli, María del Mar, Cano Valderrama, Óscar, Bravo Arribas, Coral, Bujan, Julia, Álvarez Mon, Melchor, Ortega, Miguel A., De León Luis, Juan Antonio
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/7351
Acceso en línea:https://hdl.handle.net/20.500.14352/7351
Access Level:acceso abierto
Palabra clave:614
618.1
616.9
COVID-19
Gestation
Systematic review
Maternal-perinatal outcomes
Maternal-perinatal morbidity and mortality
Maternal characteristics and COVID-19
Country profile
Medicina
Enfermedades infecciosas
Ginecología y obstetricia
Salud pública (Medicina)
32 Ciencias Médicas
3205.05 Enfermedades Infecciosas
3201.08 Ginecología
3212 Salud Pública
Descripción
Sumario:SARS-CoV-2 is the novel member of coronavirus responsible for the worldwide pandemic COVID-19, affecting all types of people. In this context, established research identified pregnant women as a susceptible group of SARS-CoV-2 infection, although there is still limited data regarding the real impact of COVID-19 in this group. With that purpose, we conducted a systematic review describing the maternal-fetal results of pregnant women infected by SARS-CoV-2, in aim to analyze the profile of the obstetric patients according to the country of origin of the publication. A total of 38 articles were included in this systematic review with 2670 patients from 7 countries, with 20 works published from China (52.6%). We reported significative differences according to the median maternal age, with Spain as the country with the highest age (34.6 years); The percentage of tabaquism; proportion of symptomatic patients in the triage; type of radiological exam (China and France conduct CT scans on all their patients in comparison to the use of chest X-Ray in the rest of the countries studied); percentages of C-sections (83.9% in China; 35.9% Spain, p < 0.001); maternal mortality rate, proportion of patients who need treatments, the use of antivirals, antibiotics, and anticoagulants as well as measurements of the newborns. Perinatal results are favorable in the majority of countries, with very low rates of vertical transmission in the majority of works. The studies collected in this review showed moderate to high index of quality. The different works describe the affectation during the first wave of the pandemic, where the pregnant woman with SARS-CoV-2 infection is generally symptomatic during the third trimester of gestation along with other factors associated with worse prognosis of the disease, such as higher age, body mass index, and further comorbidities developed during pregnancy. In the obstetric patient, proportion of C-sections are elevated together with prematurity, increasing maternal perinatal morbimortality. Differences found between countries could be based on the proper profile of the patient in each region, the period of the pandemic directly affecting how it was managed, and the variations regarding in situ medical attention.