Mitochondrial haplogroup H is related to CD4+ T cell recovery in HIV infected patients starting combination antiretroviral therapy

The mitochondrial DNA (mtDNA) seems to influence in a large number of diseases, including HIV infection. Moreover, there is a substantial inter-individual variability in the CD4+ recovery in HIV-infected patients on combination antiretroviral therapy (cART). Our study aimed to analyze the associatio...

Descripción completa

Detalles Bibliográficos
Autores: Medrano, Luz M., Gutiérrez-Rivas, Mónica, Blanco, Julià, García, Marcial, Jiménez-Sousa, María A., Pacheco, Yolanda M., Montero, Marta, Iribarren, José A., Bernal, Enrique, Martínez-Madrid, Onofre, Benito, José M., Rallón, Norma, Resino, Salvador
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/387755
Acceso en línea:http://hdl.handle.net/10261/387755
https://api.elsevier.com/content/abstract/scopus_id/85058086740
Access Level:acceso abierto
Palabra clave:mtDNA
HIV
Haplogroups
Immune reconstitution
Mitochondria
cART
Descripción
Sumario:The mitochondrial DNA (mtDNA) seems to influence in a large number of diseases, including HIV infection. Moreover, there is a substantial inter-individual variability in the CD4+ recovery in HIV-infected patients on combination antiretroviral therapy (cART). Our study aimed to analyze the association between mtDNA haplogroups and CD4+ recovery in HIV-infected patients on cART.

Similares en LA Referencia