Inter-layer functional connectivity of retinal neuronal circuits

Optogenetic therapy opens new horizons in treating blindness. To successfully implement it and restore vision, scientists use an ever-evolving set of physical methods that optically stimulate cells in the retina. This master thesis report presents a summary of the eye and retina functioning in view...

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Detalles Bibliográficos
Autor: Maslianitsyna, Anastasiia
Tipo de recurso: tesis de maestría
Fecha de publicación:2022
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/388630
Acceso en línea:https://hdl.handle.net/2117/388630
Access Level:acceso abierto
Palabra clave:Optogenetics
Retina
optogenetics
computer generated holography
retina
Optogenètica
Àrees temàtiques de la UPC::Ciències de la visió::Biologia ocular
Descripción
Sumario:Optogenetic therapy opens new horizons in treating blindness. To successfully implement it and restore vision, scientists use an ever-evolving set of physical methods that optically stimulate cells in the retina. This master thesis report presents a summary of the eye and retina functioning in view of optogenetic blindness therapy, as well as different techniques for retina illumination, including computer generated holography. The aim of the master thesis is to enhance an optical strategy for studying the neural connections in the retina. A light modulator was successfully integrated into the set-up, and its spatial resolution was studied. This is an important step in recreating retinal functionality with optogenetics therapy.