Study on the mammalian circadian rhythms modulating pharmacological properties of two secondary metabolites of lichens

Almost all living cells harbour molecular circadian clocks that synchronize physiological functions with the 24 hours day-night cycle. This physiological phenomenon is known as circadian rhythms. Light is the main zeitgeber of circadian rhythms in all the eukaryotes and prokaryotes. Upon receiving t...

Descripción completa

Detalles Bibliográficos
Autor: Srimani, Soumi
Tipo de recurso: tesis doctoral
Fecha de publicación:2025
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/117967
Acceso en línea:https://hdl.handle.net/20.500.14352/117967
Access Level:acceso abierto
Palabra clave:57.022(043.2)
Circadian rhythms
Ritmos circadianos
Metabolitos secundarios
Usnic acid
Ácido úsnico
Ácido evérnico
Secondary metabolites
Evernic acid
Farmacología (Farmacia)
3209 Farmacología
id ES_25e9f6bd7a2c29481473d2bfcb8d15a3
oai_identifier_str oai:docta.ucm.es:20.500.14352/117967
network_acronym_str ES
network_name_str España
repository_id_str
spelling Study on the mammalian circadian rhythms modulating pharmacological properties of two secondary metabolites of lichensEstudio sobre los ritmos circadianos de los mamíferos que modulan las propiedades farmacológicas de dos metabolitos secundarios de líquenesSrimani, Soumi57.022(043.2)Circadian rhythmsRitmos circadianosMetabolitos secundariosUsnic acidÁcido úsnicoÁcido evérnicoSecondary metabolitesEvernic acidFarmacología (Farmacia)3209 FarmacologíaAlmost all living cells harbour molecular circadian clocks that synchronize physiological functions with the 24 hours day-night cycle. This physiological phenomenon is known as circadian rhythms. Light is the main zeitgeber of circadian rhythms in all the eukaryotes and prokaryotes. Upon receiving the light impulse, the master pacemaker in eukaryotes and the unicellular prokaryotes initiates a new cycle of circadian rhythms that generate as well as regulates all other physiological processes and behavioural outputs like sleep-wake cycle, cell division, reproduction etc.,constituting the basic mechanism of circadian rhythms. Other than light, temperature, feeding and fasting are also important zeitgebers of circadian rhythms. The basic mechanism of circadian rhythms, also known as biological rhythms in the prokaryotes is the post-translational oscillation mechanism (PTO) whereas, that of eukaryotes is cellautonomous transcriptional-translational feed-back loops (TTFLs) along with several organism specific clock-controlled genes (CCGs) and other repressor genes...Universidad Complutense de MadridDulare Devi, Pradeep DivakarGómez-Serranillos Cuadrado, María PilarUniversidad Complutense de Madrid20252025-02-1020252025-02-10doctoral thesishttp://purl.org/coar/resource_type/c_db06info:eu-repo/semantics/doctoralThesisapplication/pdfhttps://hdl.handle.net/20.500.14352/117967reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/1179672026-06-02T12:44:21Z
dc.title.none.fl_str_mv Study on the mammalian circadian rhythms modulating pharmacological properties of two secondary metabolites of lichens
Estudio sobre los ritmos circadianos de los mamíferos que modulan las propiedades farmacológicas de dos metabolitos secundarios de líquenes
title Study on the mammalian circadian rhythms modulating pharmacological properties of two secondary metabolites of lichens
spellingShingle Study on the mammalian circadian rhythms modulating pharmacological properties of two secondary metabolites of lichens
Srimani, Soumi
57.022(043.2)
Circadian rhythms
Ritmos circadianos
Metabolitos secundarios
Usnic acid
Ácido úsnico
Ácido evérnico
Secondary metabolites
Evernic acid
Farmacología (Farmacia)
3209 Farmacología
title_short Study on the mammalian circadian rhythms modulating pharmacological properties of two secondary metabolites of lichens
title_full Study on the mammalian circadian rhythms modulating pharmacological properties of two secondary metabolites of lichens
title_fullStr Study on the mammalian circadian rhythms modulating pharmacological properties of two secondary metabolites of lichens
title_full_unstemmed Study on the mammalian circadian rhythms modulating pharmacological properties of two secondary metabolites of lichens
title_sort Study on the mammalian circadian rhythms modulating pharmacological properties of two secondary metabolites of lichens
dc.creator.none.fl_str_mv Srimani, Soumi
author Srimani, Soumi
author_facet Srimani, Soumi
author_role author
dc.contributor.none.fl_str_mv Dulare Devi, Pradeep Divakar
Gómez-Serranillos Cuadrado, María Pilar
Universidad Complutense de Madrid
dc.subject.none.fl_str_mv 57.022(043.2)
Circadian rhythms
Ritmos circadianos
Metabolitos secundarios
Usnic acid
Ácido úsnico
Ácido evérnico
Secondary metabolites
Evernic acid
Farmacología (Farmacia)
3209 Farmacología
topic 57.022(043.2)
Circadian rhythms
Ritmos circadianos
Metabolitos secundarios
Usnic acid
Ácido úsnico
Ácido evérnico
Secondary metabolites
Evernic acid
Farmacología (Farmacia)
3209 Farmacología
description Almost all living cells harbour molecular circadian clocks that synchronize physiological functions with the 24 hours day-night cycle. This physiological phenomenon is known as circadian rhythms. Light is the main zeitgeber of circadian rhythms in all the eukaryotes and prokaryotes. Upon receiving the light impulse, the master pacemaker in eukaryotes and the unicellular prokaryotes initiates a new cycle of circadian rhythms that generate as well as regulates all other physiological processes and behavioural outputs like sleep-wake cycle, cell division, reproduction etc.,constituting the basic mechanism of circadian rhythms. Other than light, temperature, feeding and fasting are also important zeitgebers of circadian rhythms. The basic mechanism of circadian rhythms, also known as biological rhythms in the prokaryotes is the post-translational oscillation mechanism (PTO) whereas, that of eukaryotes is cellautonomous transcriptional-translational feed-back loops (TTFLs) along with several organism specific clock-controlled genes (CCGs) and other repressor genes...
publishDate 2025
dc.date.none.fl_str_mv 2025
2025-02-10
2025
2025-02-10
dc.type.none.fl_str_mv doctoral thesis
http://purl.org/coar/resource_type/c_db06
dc.type.openaire.fl_str_mv info:eu-repo/semantics/doctoralThesis
format doctoralThesis
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/117967
url https://hdl.handle.net/20.500.14352/117967
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Complutense de Madrid
publisher.none.fl_str_mv Universidad Complutense de Madrid
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869404790543351808
score 15,812455

Similares en LA Referencia