| Sumario: | Multimedia component 1: Table S1. Composition of the saline solution for the inoculum, the buffering saline solution and the nutritive medium, and commercial brands for each reagent. Table S2. Mix of internal standards used for UHPLC-Q/TOF MS (ESI-C18) analysis. All of them were purchased from Merck (Darmstadt, Germany). Table S3. Individual compound concentration (µg/g ODP) and relative values (% of initial concentration compared to 0 h) of betalains and phenolic compounds during in vitro fermentation of Opuntia stricta var. dillenii pulp extracts under abiotic (ODP) and microbial (ODP+M) conditions. Table S4. Average peak intensity and relative values (% of initial concentration compared to 0 h) of the individual non-target compounds during in vitro fermentation of Opuntia stricta var. dillenii pulp extracts under abiotic (ODP) and microbial (ODP+M) conditions. Fig. S1. Chromatograms detected at 280, 370, 535 and 480 nm of culture medium (CR) (a)) and the medium inoculated with human gut microbiota (b)). No compounds of interest were detected on these samples. Fig. S2. Chromatograms detected at 280, 370, 535 and 480 nm of ODP extract (a)), ODP + M at time 0 h of incubation (b)), and ODP + M at time 48 h of incubation (c)). Peak numbers are as follows 1: Piscidic acid; 2: Betanin; 3: Isobetanin; 4: 2'-O-apiosyl-4-O-phyllocactin; 5: 5''-O-E-sinapoyl-2'-apyosil-phyllocactin; 6: Neobetanin; 7: IG1; and 8: IG2.
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