Resin-modified calcium silicate-based materials versus conventional formulations in primary teeth: a systematic review and meta-analysis of clinical and radiographic outcomes of vital pulp therapy procedures in pediatric dentistry

Vital pulp therapy comprises a group of procedures whose use in the primary dentition is increasingly supported in pediatric dentistry. The clinical management of pediatric patients requires biomaterials that provide precision, ease of handling, and reduced chairside time; in this context, resin-mod...

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Detalles Bibliográficos
Autores: Cabrera Fernández, Alberto, Dominguez-Dominguez, Laura, Pérez Pérez, Antonio, Santos, João Miguel Marques dos, Díaz-Cuenca, Aránzazu, Sánchez Margalet, Víctor, Sequeira, Diana B., Segura Egea, Juan José, Martín González, Jenifer
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2026
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:dnet:idus________::5fe960e1f3a579e52d57983c36818b55
Acceso en línea:https://hdl.handle.net/11441/184040
https://doi.org/10.3390/jfb17030147
Access Level:acceso abierto
Palabra clave:Vital pulp therapy
Pediatric dentistry
Resin-modified calcium silicate-based materials
Theracal LC
Indirect pulp capping
Pulpotomy
Meta-analysis
Primary teeth
Descripción
Sumario:Vital pulp therapy comprises a group of procedures whose use in the primary dentition is increasingly supported in pediatric dentistry. The clinical management of pediatric patients requires biomaterials that provide precision, ease of handling, and reduced chairside time; in this context, resin-modified calcium silicate-based materials (RM-CSCs) have been introduced as an alternative to conventional calcium silicate formulations. This systematic review and meta-analysis aimed to evaluate the clinical effectiveness of RM-CSCs compared with non-resin calcium silicate-based materials in vital pulp therapy performed in primary teeth. A systematic search was conducted in MEDLINE, Scopus, Embase, and Web of Science in accordance with PRISMA guidelines. Randomized clinical trials were included, the risk of bias was assessed using the RoB 2 tool, and the certainty of evidence was evaluated using the GRADE approach. Of the 605 records initially identified, nine randomized clinical trials were ultimately included, all of which evaluated TheraCal LC as the RM-CSC. Meta-analyses were performed for vital pulp therapy overall and for procedure-specific subanalyses, including indirect pulp capping and pulpotomy. None of the meta-analyses demonstrated statistically significant differences between RM-CSCs and non-resin calcium silicate-based materials in terms of clinical or radiographic success. Therefore, the available evidence supports the use of TheraCal LC as an effective option for indirect pulp capping in primary teeth; however, its use in pulpotomy should be interpreted with caution until further randomized clinical trials become available.