Glutathione oxidation correlates with one- lung ventilation time and PO2/FiO2 ratio during pulmonary lobectomy

During lung lobectomy, the operated lung completely collapses with simultaneous hypoxic pulmonary vasoconstriction, followed by expansion and reperfusion. Here, we investigated glutathione oxidation and lipoperoxidation in patients undergoing lung lobectomy, during one-lung ventilation (OLV) and aft...

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Detalhes bibliográficos
Autores: García-de-la-Asunción, José, García-del-Olmo, Eva, Galan, Genaro, Guijarro, Ricardo, Martí, Francisco, Badenes, Rafael, Perez-Griera, Jaume, Duca, Alejandro, Delgado, Carlos, Carbonell, Jose, Belda, Javier
Formato: artículo
Fecha de publicación:2016
País:España
Recursos:Universidad Católica de Valencia San Vicente Mártir
Repositorio:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
Idioma:inglés
OAI Identifier:oai:riucv.ucv.es:20.500.12466/6813
Acesso em linha:https://hdl.handle.net/20.500.12466/6813
Access Level:acceso abierto
Palavra-chave:Lung lobectomy
One-lung ventilation
Oxidative lung injury
Glutathione oxidation
Glutathione redox potential
Malondialdehyde
32 Ciencias Médicas
Descrição
Resumo:During lung lobectomy, the operated lung completely collapses with simultaneous hypoxic pulmonary vasoconstriction, followed by expansion and reperfusion. Here, we investigated glutathione oxidation and lipoperoxidation in patients undergoing lung lobectomy, during one-lung ventilation (OLV) and after resuming two-lung ventilation (TLV), and examined the relationship with OLV duration.

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