Supramolecular strategies for intracellular delivery and design of new thermoresponsive materials

In this Ph.D. dissertation, we have applied supramolecular strategies to promote intracellular delivery of diverse molecules and design potential thermoresponsive systems. Host-guest chemistry has been exploited to encapsulate and deliver different anionic probes such as pyranine, as well as anionic...

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Bibliographic Details
Author: Fernández Caro, Héctor
Format: doctoral thesis
Publication Date:2020
Country:España
Institution:Universidad de Santiago de Compostela (USC)
Repository:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Language:English
OAI Identifier:oai:minerva.usc.gal:10347/24499
Online Access:http://hdl.handle.net/10347/24499
Access Level:Open access
Keyword:Materias::Investigación::23 Química::2302 Bioquímica::230224 Péptidos
Description
Summary:In this Ph.D. dissertation, we have applied supramolecular strategies to promote intracellular delivery of diverse molecules and design potential thermoresponsive systems. Host-guest chemistry has been exploited to encapsulate and deliver different anionic probes such as pyranine, as well as anionic peptides with low self-delivery efficiency. Finally, we have designed potential thermoresponsive supramolecular materials based on self-assembling cyclic peptide nanotubes (SCPNs).