Comparison of the volumetric composition of lamellar bone and the woven bone of calluses

Woven tissue is mainly present in the bone callus, formed very rapidly either after a fracture or in distraction processes. This high formation speed is probably responsible for its disorganized microstructure and this, in turn, for its low stiffness. Nonetheless, the singular volumetric composition...

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Autores: Martínez Reina, Francisco Javier, García Rodríguez, Javier, Mora Macías, Juan, Domínguez Abascal, Jaime, Reina Romo, Esther
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2018
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/151984
Acceso en línea:https://hdl.handle.net/11441/151984
https://doi.org/10.1177/0954411918784085
Access Level:acceso abierto
Palabra clave:Bone transport
Callus
Mineral content
Volumetric composition
Woven bone
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spelling Comparison of the volumetric composition of lamellar bone and the woven bone of callusesMartínez Reina, Francisco JavierGarcía Rodríguez, JavierMora Macías, JuanDomínguez Abascal, JaimeReina Romo, EstherBone transportCallusMineral contentVolumetric compositionWoven boneWoven tissue is mainly present in the bone callus, formed very rapidly either after a fracture or in distraction processes. This high formation speed is probably responsible for its disorganized microstructure and this, in turn, for its low stiffness. Nonetheless, the singular volumetric composition of this tissue may also play a key role in its mechanical properties. The volumetric composition of woven tissue extracted from the bone transport callus of sheep was investigated and compared with that of the lamellar tissue extracted from the cortical shell of the same bone. Significant differences were found in the mineral and water contents, but they can be due to the different ages of both tissues, which affects the mineral/water ratio. However, the content in organic phase remains more or less constant throughout the mineralization process and has proven to be a good variable to measure the different composition of both tissues, being that content significantly higher in woven tissue. This may be linked to the abnormally high concentration of osteocytes in this tissue, which is likely a consequence of the more abundant presence of osteoblasts secreting osteoid and burying other osteoblasts, which then differentiate into osteocytes. This would explain the high formation rate of woven tissue, useful to recover the short-term stability of the bone. Nonetheless, the more abundant presence of organic phase prevents the woven tissue from reaching a stiffness similar to that of lamellar tissue in the long term, when it is fully mineralized.SAGEIngeniería Mecánica y FabricaciónTEP111: Ingeniería MecánicaMinisterio de Economía y Competitividad (MINECO). España2018info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/151984https://doi.org/10.1177/0954411918784085reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)InglésJournal of Engineering in Medicine, 232 (7), 682-689.DPI2014-58233-Phttps://journals.sagepub.com/doi/10.1177/0954411918784085info:eu-repo/semantics/openAccessoai:idus.us.es:11441/1519842026-06-17T12:51:07Z
dc.title.none.fl_str_mv Comparison of the volumetric composition of lamellar bone and the woven bone of calluses
title Comparison of the volumetric composition of lamellar bone and the woven bone of calluses
spellingShingle Comparison of the volumetric composition of lamellar bone and the woven bone of calluses
Martínez Reina, Francisco Javier
Bone transport
Callus
Mineral content
Volumetric composition
Woven bone
title_short Comparison of the volumetric composition of lamellar bone and the woven bone of calluses
title_full Comparison of the volumetric composition of lamellar bone and the woven bone of calluses
title_fullStr Comparison of the volumetric composition of lamellar bone and the woven bone of calluses
title_full_unstemmed Comparison of the volumetric composition of lamellar bone and the woven bone of calluses
title_sort Comparison of the volumetric composition of lamellar bone and the woven bone of calluses
dc.creator.none.fl_str_mv Martínez Reina, Francisco Javier
García Rodríguez, Javier
Mora Macías, Juan
Domínguez Abascal, Jaime
Reina Romo, Esther
author Martínez Reina, Francisco Javier
author_facet Martínez Reina, Francisco Javier
García Rodríguez, Javier
Mora Macías, Juan
Domínguez Abascal, Jaime
Reina Romo, Esther
author_role author
author2 García Rodríguez, Javier
Mora Macías, Juan
Domínguez Abascal, Jaime
Reina Romo, Esther
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Ingeniería Mecánica y Fabricación
TEP111: Ingeniería Mecánica
Ministerio de Economía y Competitividad (MINECO). España
dc.subject.none.fl_str_mv Bone transport
Callus
Mineral content
Volumetric composition
Woven bone
topic Bone transport
Callus
Mineral content
Volumetric composition
Woven bone
description Woven tissue is mainly present in the bone callus, formed very rapidly either after a fracture or in distraction processes. This high formation speed is probably responsible for its disorganized microstructure and this, in turn, for its low stiffness. Nonetheless, the singular volumetric composition of this tissue may also play a key role in its mechanical properties. The volumetric composition of woven tissue extracted from the bone transport callus of sheep was investigated and compared with that of the lamellar tissue extracted from the cortical shell of the same bone. Significant differences were found in the mineral and water contents, but they can be due to the different ages of both tissues, which affects the mineral/water ratio. However, the content in organic phase remains more or less constant throughout the mineralization process and has proven to be a good variable to measure the different composition of both tissues, being that content significantly higher in woven tissue. This may be linked to the abnormally high concentration of osteocytes in this tissue, which is likely a consequence of the more abundant presence of osteoblasts secreting osteoid and burying other osteoblasts, which then differentiate into osteocytes. This would explain the high formation rate of woven tissue, useful to recover the short-term stability of the bone. Nonetheless, the more abundant presence of organic phase prevents the woven tissue from reaching a stiffness similar to that of lamellar tissue in the long term, when it is fully mineralized.
publishDate 2018
dc.date.none.fl_str_mv 2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/151984
https://doi.org/10.1177/0954411918784085
url https://hdl.handle.net/11441/151984
https://doi.org/10.1177/0954411918784085
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Journal of Engineering in Medicine, 232 (7), 682-689.
DPI2014-58233-P
https://journals.sagepub.com/doi/10.1177/0954411918784085
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv SAGE
publisher.none.fl_str_mv SAGE
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
repository.mail.fl_str_mv
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