On the influence of structural and chemical properties on the elastic modulus of woven bone under healing

Woven bone, a heterogeneous and temporary tissue in bone regeneration, is remodeled by osteoblastic and osteoclastic activity and shaped by mechanical stress to restore healthy tissue properties. Characterizing this tissue at different length scales is crucial for developing micromechanical models t...

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Detalles Bibliográficos
Autores: Blázquez Carmona, Pablo, Mora Macías, Juan, Pajares, Antonia, Mármol, Álvaro, Reina Romo, Esther
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/165976
Acceso en línea:https://hdl.handle.net/11441/165976
https://doi.org/10.3389/fbioe.2024.1476473
Access Level:acceso abierto
Palabra clave:Composition
Distraction osteogenesis
Elastic modulus
Micro-CT
Nanoindentation
Power law
Raman sprectroscopy
Woven bone
Descripción
Sumario:Woven bone, a heterogeneous and temporary tissue in bone regeneration, is remodeled by osteoblastic and osteoclastic activity and shaped by mechanical stress to restore healthy tissue properties. Characterizing this tissue at different length scales is crucial for developing micromechanical models that optimize mechanical parameters, thereby controlling regeneration and preventing non-unions.