Carotenoid Biosynthesis in Fusarium

16 Páginas; 5 Figuras

Detalhes bibliográficos
Autores: Ávalos, Javier, Pardo Medina, Javier, Parra Rivero, Obdulia, Ruger Herreros, Macarena, Rodríguez Ortiz, Roberto, Hornero-Méndez, Dámaso, Limón, M. Carmen
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/152575
Acesso em linha:http://hdl.handle.net/10261/152575
Access Level:acceso abierto
Palavra-chave:Neurosporaxanthin
Xanthophyll
Apocarotenoids
Retinal
Torulene
Photoinduction
RING-Finger protein
Carotenoid gene cluster
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spelling Carotenoid Biosynthesis in FusariumÁvalos, JavierPardo Medina, JavierParra Rivero, ObduliaRuger Herreros, MacarenaRodríguez Ortiz, RobertoHornero-Méndez, DámasoLimón, M. CarmenNeurosporaxanthinXanthophyllApocarotenoidsRetinalTorulenePhotoinductionRING-Finger proteinCarotenoid gene cluster16 Páginas; 5 FigurasMany fungi of the genus Fusarium stand out for the complexity of their secondary metabolism. Individual species may differ in their metabolic capacities, but they usually share the ability to synthesize carotenoids, a family of hydrophobic terpenoid pigments widely distributed in nature. Early studies on carotenoid biosynthesis in Fusarium aquaeductuum have been recently extended in Fusarium fujikuroi and Fusarium oxysporum, well-known biotechnological and phytopathogenic models, respectively. The major Fusarium carotenoid is neurosporaxanthin, a carboxylic xanthophyll synthesized from geranylgeranyl pyrophosphate through the activity of four enzymes, encoded by the genes carRA, carB, carT and carD. These fungi produce also minor amounts of β-carotene, which may be cleaved by the CarX oxygenase to produce retinal, the rhodopsin’s chromophore. The genes needed to produce retinal are organized in a gene cluster with a rhodopsin gene, while other carotenoid genes are not linked. In the investigated Fusarium species, the synthesis of carotenoids is induced by light through the transcriptional induction of the structural genes. In some species, deep-pigmented mutants with up-regulated expression of these genes are affected in the regulatory gene carS. The molecular mechanisms underlying the control by light and by the CarS protein are currently under investigation.We thank the Spanish Government (projects BIO2012-39716, BIO2015-69613-R, AGL2014-53195R and CaRed Network BIO2015-71703-REDT) and Junta de Andalucía (project CTS-6638) for financial support.We acknowledge support by the CSIC Open Access Publication Initiative through its Unit of Information Resources for Research (URICI).Peer reviewedMultidisciplinary Digital Publishing InstituteMinisterio de Economía y Competitividad (España)Junta de AndalucíaConsejo Superior de Investigaciones Científicas (España)Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]201720172017info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/152575reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2014-53195-Rhttp://dx.doi.org/10.3390/jof3030039Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/1525752026-05-22T06:33:51Z
dc.title.none.fl_str_mv Carotenoid Biosynthesis in Fusarium
title Carotenoid Biosynthesis in Fusarium
spellingShingle Carotenoid Biosynthesis in Fusarium
Ávalos, Javier
Neurosporaxanthin
Xanthophyll
Apocarotenoids
Retinal
Torulene
Photoinduction
RING-Finger protein
Carotenoid gene cluster
title_short Carotenoid Biosynthesis in Fusarium
title_full Carotenoid Biosynthesis in Fusarium
title_fullStr Carotenoid Biosynthesis in Fusarium
title_full_unstemmed Carotenoid Biosynthesis in Fusarium
title_sort Carotenoid Biosynthesis in Fusarium
dc.creator.none.fl_str_mv Ávalos, Javier
Pardo Medina, Javier
Parra Rivero, Obdulia
Ruger Herreros, Macarena
Rodríguez Ortiz, Roberto
Hornero-Méndez, Dámaso
Limón, M. Carmen
author Ávalos, Javier
author_facet Ávalos, Javier
Pardo Medina, Javier
Parra Rivero, Obdulia
Ruger Herreros, Macarena
Rodríguez Ortiz, Roberto
Hornero-Méndez, Dámaso
Limón, M. Carmen
author_role author
author2 Pardo Medina, Javier
Parra Rivero, Obdulia
Ruger Herreros, Macarena
Rodríguez Ortiz, Roberto
Hornero-Méndez, Dámaso
Limón, M. Carmen
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Ministerio de Economía y Competitividad (España)
Junta de Andalucía
Consejo Superior de Investigaciones Científicas (España)
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Neurosporaxanthin
Xanthophyll
Apocarotenoids
Retinal
Torulene
Photoinduction
RING-Finger protein
Carotenoid gene cluster
topic Neurosporaxanthin
Xanthophyll
Apocarotenoids
Retinal
Torulene
Photoinduction
RING-Finger protein
Carotenoid gene cluster
description 16 Páginas; 5 Figuras
publishDate 2017
dc.date.none.fl_str_mv 2017
2017
2017
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/152575
url http://hdl.handle.net/10261/152575
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2014-53195-R
http://dx.doi.org/10.3390/jof3030039
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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