Enantioselective Photochemical Organocascade Catalysis

Reported herein is a photochemical cascade process that combines the excited-state and ground-state reactivity of chiral organocatalytic intermediates. This strategy directly converts racemic cyclopropanols and a,b-unsaturated alde- hydes into stereochemically dense cyclopentanols with exqui- site s...

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Detalles Bibliográficos
Autores: Woz ́niak, Łukasz, Magagnano, Giandomenico, Melchiorre, Paolo
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2017
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2072/350696
Acceso en línea:http://hdl.handle.net/2072/350696
https://doi.org/10.1002/anie.201711397
Access Level:acceso abierto
Palabra clave:54
Descripción
Sumario:Reported herein is a photochemical cascade process that combines the excited-state and ground-state reactivity of chiral organocatalytic intermediates. This strategy directly converts racemic cyclopropanols and a,b-unsaturated alde- hydes into stereochemically dense cyclopentanols with exqui- site stereoselectivity. Mechanistic investigations have enabled elucidating the origin of the stereoconvergence, which is governed by a kinetic resolution process.