Are obesity and physical fitness associated with cardiovascular disease risk in adolescents with Down syndrome? The longitudinal UP&DOWN study

Introduction: The aims of this study were to examine cross-sectional, and longitudinal association of different measures of obesity and physical fitness with cardiovascular disease (CVD) risk factors in adolescents with Down syndrome. Methods: Longitudinal analysis included 90 adolescents with Down...

Descripción completa

Detalles Bibliográficos
Autores: Izquierdo-Gómez, Rocio, Esteban-Cornejo, Irene, Cabanas-Sánchez, Verónica, Marcos, Ascensión, Gómez-Martínez, Sonia, Castro-Piñero, José, Veiga Núñez, Óscar Luis
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/714810
Acceso en línea:http://hdl.handle.net/10486/714810
https://dx.doi.org/10.3109/13668250.2023.2188876
Access Level:acceso abierto
Palabra clave:Down syndrome
obesity
physical fitness
Educación
Descripción
Sumario:Introduction: The aims of this study were to examine cross-sectional, and longitudinal association of different measures of obesity and physical fitness with cardiovascular disease (CVD) risk factors in adolescents with Down syndrome. Methods: Longitudinal analysis included 90 adolescents with Down syndrome. Obesity and physical fitness were measured following the ALPHA battery. Blood pressure and blood samplings (glucose, total cholesterol, high-density lipoprotein cholesterol, and serum lipid triglycerides levels (mg/dl) were determinated. Results: In cross-sectional analyses, obesity was positively associated with single CVD risk factors and CVD risk factor index (all p <.05). In the prospective analyses, obesity was not associated with single CVD risk factors, but components of physical fitness at baseline impact in some single CVD risk factors (all p <.05). Conclusion: Obesity might be more strongly related to current cardiovascular-health, while components of physical fitness might be more related to future cardiovascular-health in adolescents with Down syndrome