Complete and de novo assembly of the Leishmania braziliensis (M2904) genome

Leishmania braziliensis is the etiological agent of American mucosal leishmaniasis, one of the most severe clinical forms of leishmaniasis. Here, we report the assembly of the L. braziliensis (M2904) genome into 35 continuous chromosomes. Also, the annotation of 8395 genes is provided. The public av...

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Detalles Bibliográficos
Autores: González-de la Fuente, Sandra, Camacho, Esther, Peiró-Pastor, Ramón, Rastrojo Lastras, Alberto, Carrasco-Ramiro, Fernando, Aguado, Begoña, Requena Rolania, José María
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/718723
Acceso en línea:http://hdl.handle.net/10486/718723
https://dx.doi.org/10.1590/0074-02760180438
Access Level:acceso abierto
Palabra clave:Genome assembly
next generation sequencing
Illumina short reads
PacBio long reads
chromosomes
gene annotation
Biología y Biomedicina / Biología
Descripción
Sumario:Leishmania braziliensis is the etiological agent of American mucosal leishmaniasis, one of the most severe clinical forms of leishmaniasis. Here, we report the assembly of the L. braziliensis (M2904) genome into 35 continuous chromosomes. Also, the annotation of 8395 genes is provided. The public availability of this information will contribute to a better knowledge of this pathogen and help in the search for vaccines and novel drug targets aimed to control the disease caused by this Leishmania species