Complete and de novo assembly of the Leishmania braziliensis (M2904) genome

Leishmania braziliensis is the etiological agent of American mucosal leishmaniasis, one of the most severe clinical forms of leishmaniasis. Here, we report the assembly of the L. braziliensis (M2904) genome into 35 continuous chromosomes. Also, the annotation of 8395 genes is provided. The public av...

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Detalles Bibliográficos
Autores: González-De la Fuente, Sandra, Camacho, Esther, Peiró-Pastor, Ramón, Rastrojo, Alberto, Carrasco-Ramiro, Fernando, Aguado, Begoña, Requena, José María
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/217186
Acceso en línea:http://hdl.handle.net/10261/217186
Access Level:acceso abierto
Palabra clave:Genome assembly
Next generation sequencing
Illumina short reads
PacBio long reads
Chromosomes
Gene annotation
Descripción
Sumario:Leishmania braziliensis is the etiological agent of American mucosal leishmaniasis, one of the most severe clinical forms of leishmaniasis. Here, we report the assembly of the L. braziliensis (M2904) genome into 35 continuous chromosomes. Also, the annotation of 8395 genes is provided. The public availability of this information will contribute to a better knowledge of this pathogen and help in the search for vaccines and novel drug targets aimed to control the disease caused by this Leishmania species.