Catalytic activation of diboron reagents towards their addition to alkenes: experimental and theoretical approach
The organoborane products are highly used in a broad number of fields, from their use in medicine as a 10B carrier for neutron capture therapy, or other molecules with biological activity, to their use as functional molecules such as polymers. Importantly, organoboranes are very versatile and powerf...
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| Formato: | tesis doctoral |
| Estado: | Versión publicada |
| Fecha de publicación: | 2012 |
| País: | España |
| Recursos: | Universitat Rovira i virgili (URV) |
| Repositorio: | Repositori Institucional de la Universitat Rovira i Virgili |
| OAI Identifier: | oai:urv.cat:TDX:1145 |
| Acesso em linha: | https://hdl.handle.net/20.500.11797/TDX1145 http://hdl.handle.net/10803/97206 |
| Access Level: | acceso abierto |
| Palavra-chave: | 547 - Química orgànica 546 - Química inorgànica 54 - Química |
| Resumo: | The organoborane products are highly used in a broad number of fields, from their use in medicine as a 10B carrier for neutron capture therapy, or other molecules with biological activity, to their use as functional molecules such as polymers. Importantly, organoboranes are very versatile and powerful intermediates in the synthesis of high value products. This thesis focuses on the development of novel methodologies for catalytic boron addition to alkenes, with particular attention to the understanding of the activation mode of the diboron reagent and the mechanism of their addition to olefins. For this purpose NMR studies together with DFT (Density Functional Theory) calculations are carried out. |
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