Carbohydrate quality index and mortality risk in older adults at high cardiovascular risk

Carbohydrate quality may influence long-term health, but its relationship with mortality in older adults remains unclear. We examined the association between carbohydrate quality and all-cause and cause-specific mortality in 7210 older adults at high cardiovascular disease risk from the PREDIMED tri...

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Detalhes bibliográficos
Autores: Vázquez-Lorente, Héctor, Nishi, Stephanie K., Shyam, Sangeetha, Martínez-González, Miguel A., Corella, Dolores, Estruch, Ramón, Ros, Emilio, Gómez-Gracia, Enrique, Fiol Sala, Miquel, Lapetra, José, Serra-Majem, Lluís, Esteve-Luque, Virginia, Babio, Nancy, Fitó, Montserrat, Toledo, Estefanía, Sorlí, José V., Zazpe, Itziar, Salas-Salvadó, Jordi
Formato: artículo
Fecha de publicación:2026
País:España
Recursos:Conselleria de Salut i Consum del Govern de les Illes Balears
Repositorio:Docusalut
Idioma:inglés
OAI Identifier:oai:dnet:docusalut___::931f953ad9bd15242f2e978a673b4780
Acesso em linha:https://hdl.handle.net/20.500.13003/27498
Access Level:acceso abierto
Palavra-chave:Carbohydrate quality index
mortality risk
older adults
high cardiovascular risk
Descrição
Resumo:Carbohydrate quality may influence long-term health, but its relationship with mortality in older adults remains unclear. We examined the association between carbohydrate quality and all-cause and cause-specific mortality in 7210 older adults at high cardiovascular disease risk from the PREDIMED trial. Carbohydrate quality was assessed using a cumulative average carbohydrate quality index (CQI), combining glycemic index, dietary fiber intake, whole-grain-to-total grain ratio, and solid carbohydrate-to-total carbohydrate ratio, derived from repeated validated food frequency questionnaires. During a median follow-up of 6 years, 425 deaths occurred, including 103 cardiovascular, 169 cancer, and 153 other-cause deaths. In multivariable-adjusted Cox regression models, higher CQI was associated with lower cancer mortality, while participants in the lowest CQI quintile had higher risks of all-cause and cancer mortality compared with those with higher CQI scores. Dietary fiber and whole-grain intake appeared to be the main CQI components driving these associations. These findings suggest that improving carbohydrate quality, particularly through higher intake of fiber-rich and whole-grain foods, may contribute to lower mortality risk in older adults at high cardiovascular risk.

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