Fructose-1,6-biphosphate in rat intestinal preconditioning: involvement of nitric oxide
[BACKGROUND AND AIMS] Inhibition of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) by nitric oxide (NO) in intestinal preconditioning could modify the rate of formation of glycolytic intermediates. Fructose-1,6-biphosphate (F16BP) is a glycolytic intermediate that protects tissue from ischaemia/re...
| Autores: | , , , |
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| Formato: | artículo |
| Fecha de publicación: | 2001 |
| País: | España |
| Recursos: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/2972 |
| Acesso em linha: | http://dx.doi.org/10.1136/gut.48.2.168 http://hdl.handle.net/10261/2972 |
| Access Level: | acceso abierto |
| Palavra-chave: | Fructose-1,6-biphosphate Glyceraldehyde- 3-phosphate dehydrogenase Intestinal preconditioning Ischaemia/reperfusion injury Nitric Oxide |
| Resumo: | [BACKGROUND AND AIMS] Inhibition of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) by nitric oxide (NO) in intestinal preconditioning could modify the rate of formation of glycolytic intermediates. Fructose-1,6-biphosphate (F16BP) is a glycolytic intermediate that protects tissue from ischaemia/reperfusion injury. We evaluated if F16BP may be endogenously accumulated as a consequence of GAPDH inhibition by NO during intestinal preconditioning in rats. |
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