Therapeutic Properties and Use of Extra Virgin Olive Oil in Clinical Nutrition: A Narrative Review and Literature Update

Extra virgin olive oil (EVOO) is a cornerstone of the Mediterranean diet (MedD). In this narrative review, we synthesize and illustrate the various characteristics and clinical applications of EVOO and its components-such as oleic acid, hydroxytyrosol, and oleuropein-in the field of clinical nutriti...

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Bibliographic Details
Authors: Jiménez-Sánchez, Andrés, Martínez-Ortega, Antonio J., Remón-Ruiz, Pablo, Piñar-Gutiérrez, Ana, Pereira-Cunill, José Luis, García-Luna, Pedro Pablo
Format: article
Status:Published version
Publication Date:2022
Country:España
Institution:Consejo Superior de Investigaciones Científicas (CSIC)
Repository:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/306899
Online Access:http://hdl.handle.net/10261/306899
https://api.elsevier.com/content/abstract/scopus_id/85127378814
Access Level:Open access
Keyword:Parenteral nutrition
Mediterranean diet
Cancer
Diabetes mellitus
Enteral nutrition
Hydroxytyrosol
Oleic acid
Oleocanthal
Oleuropein
Olive oil
Description
Summary:Extra virgin olive oil (EVOO) is a cornerstone of the Mediterranean diet (MedD). In this narrative review, we synthesize and illustrate the various characteristics and clinical applications of EVOO and its components-such as oleic acid, hydroxytyrosol, and oleuropein-in the field of clinical nutrition and dietetics. The evidence is split into diet therapy, oleic acid-based enteral nutrition formulations and oral supplementation formulations, oleic acid-based parenteral nutrition, and nutraceutical supplementation of minor components of EVOO. EVOO has diverse beneficial health properties, and current evidence supports the use of whole EVOO in diet therapy and the supplementation of its minor components to improve cardiovascular health, lipoprotein metabolism, and diabetes mellitus in clinical nutrition. Nevertheless, more intervention studies in humans are needed to chisel specific recommendations for its therapeutic use through different formulations in other specific diseases and clinical populations.