ISG15 as a prognostic biomarker in solitary fibrous tumour

[Background] Solitary fibrous tumour (SFT) is a rare mesenchymal malignancy that lacks robust prognostic and predictive biomarkers. Interferon-stimulated gene 15 (ISG15) is a ubiquitin-like modifier, associated with tumour progression, and with poor survival of SFT patients, as previous published by...

Descripción completa

Detalles Bibliográficos
Autores: Mondaza-Hernández, José L., Moura, David S., López-Álvarez, María, Sánchez-Bustos, Paloma, Blanco-Alcaina, Elena, Castilla, Carolina, Collini, Paola, Merino-García, Jose, Zamora, Jorge, Carrillo-García, Jaime, Maestro, Roberta, Hindi, Nadia, García-Foncillas, Jesús, Martín-Broto, Javier
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/306571
Acceso en línea:http://hdl.handle.net/10261/306571
https://api.elsevier.com/content/abstract/scopus_id/85134520288
Access Level:acceso abierto
Palabra clave:Biomarkers
Cancer stem cells
Drug resistance
ISG15
Solitary fibrous tumour
Descripción
Sumario:[Background] Solitary fibrous tumour (SFT) is a rare mesenchymal malignancy that lacks robust prognostic and predictive biomarkers. Interferon-stimulated gene 15 (ISG15) is a ubiquitin-like modifier, associated with tumour progression, and with poor survival of SFT patients, as previous published by our group. Here, we describe the role of ISG15 in the biology of this rare tumour.

Similares en LA Referencia