Monocyte Subsets and Serum Inflammatory and Bone-Associated Markers in Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma

© 2021 by the authors.

Detalhes bibliográficos
Autores: Damasceno, Daniela, Almeida, Julia, Teodosio, Cristina, Sanoja-Flores, Luzalba, Mayado, Andrea, Pérez-Pons, Alba, Puig, Noemi, Arana, Paula, Paiva, Bruno, Solano, Fernando, Romero, Alfonso, Matarraz, Sergio, Bossche, Wouter B. L.van den, Flores-Montero, Juan, Durie, B., Dongen, J. J. M. van, Orfao, Alberto
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2021
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/261847
Acesso em linha:http://hdl.handle.net/10261/261847
Access Level:Acceso aberto
Palavra-chave:Plasma cell neoplasms
MGUS
Multiple myeloma
Monocytes
FcεRI monocytes
Tumor microenvironment
Inflammatory cytokines
Immunosenescence
Bone markers
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spelling Monocyte Subsets and Serum Inflammatory and Bone-Associated Markers in Monoclonal Gammopathy of Undetermined Significance and Multiple MyelomaDamasceno, DanielaAlmeida, JuliaTeodosio, CristinaSanoja-Flores, LuzalbaMayado, AndreaPérez-Pons, AlbaPuig, NoemiArana, PaulaPaiva, BrunoSolano, FernandoRomero, AlfonsoMatarraz, SergioBossche, Wouter B. L.van denFlores-Montero, JuanDurie, B.Dongen, J. J. M. vanOrfao, AlbertoPlasma cell neoplasmsMGUSMultiple myelomaMonocytesFcεRI monocytesTumor microenvironmentInflammatory cytokinesImmunosenescenceBone markers© 2021 by the authors.Monocyte/macrophages have been shown to be altered in monoclonal gammopathy of undetermined significance (MGUS), smoldering (SMM) and active multiple myeloma (MM), with an impact on the disruption of the homeostasis of the normal bone marrow (BM) microenvironment.This research was funded by the Biomedical Research Networking Center Consortium CIBER-CIBERONC (CB16/12/00400, CB16/12/00369 and CB16/12/00233-FEDER), PI13/01412- FEDER, from the Instituto de Salud Carlos III (ISCIII), Ministerio de Economía y Competitividad, Madrid, Spain; the European Research Council (ERC) under the European Union’s Horizon 2020 Research and Innovation Programme (grant agreement ERC-2015-AdG 695655 (TiMaScan); and the Black Swan Research Initiative of the International Myeloma Foundation (Los Angeles, CA, USA), (grant IMF13/IMF16)Multidisciplinary Digital Publishing InstituteCentro de Investigación Biomédica en Red Cáncer (España)Instituto de Salud Carlos IIIEuropean CommissionMinisterio de Economía y Competitividad (España)European Research CouncilEuropean CommissionInternational Myeloma FoundationConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]2022202220212022info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/261847reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/EC/H2020/695655http://dx.doi.org/10.3390/cancers13061454Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2618472026-05-22T06:33:51Z
dc.title.none.fl_str_mv Monocyte Subsets and Serum Inflammatory and Bone-Associated Markers in Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma
title Monocyte Subsets and Serum Inflammatory and Bone-Associated Markers in Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma
spellingShingle Monocyte Subsets and Serum Inflammatory and Bone-Associated Markers in Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma
Damasceno, Daniela
Plasma cell neoplasms
MGUS
Multiple myeloma
Monocytes
FcεRI monocytes
Tumor microenvironment
Inflammatory cytokines
Immunosenescence
Bone markers
title_short Monocyte Subsets and Serum Inflammatory and Bone-Associated Markers in Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma
title_full Monocyte Subsets and Serum Inflammatory and Bone-Associated Markers in Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma
title_fullStr Monocyte Subsets and Serum Inflammatory and Bone-Associated Markers in Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma
title_full_unstemmed Monocyte Subsets and Serum Inflammatory and Bone-Associated Markers in Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma
title_sort Monocyte Subsets and Serum Inflammatory and Bone-Associated Markers in Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma
dc.creator.none.fl_str_mv Damasceno, Daniela
Almeida, Julia
Teodosio, Cristina
Sanoja-Flores, Luzalba
Mayado, Andrea
Pérez-Pons, Alba
Puig, Noemi
Arana, Paula
Paiva, Bruno
Solano, Fernando
Romero, Alfonso
Matarraz, Sergio
Bossche, Wouter B. L.van den
Flores-Montero, Juan
Durie, B.
Dongen, J. J. M. van
Orfao, Alberto
author Damasceno, Daniela
author_facet Damasceno, Daniela
Almeida, Julia
Teodosio, Cristina
Sanoja-Flores, Luzalba
Mayado, Andrea
Pérez-Pons, Alba
Puig, Noemi
Arana, Paula
Paiva, Bruno
Solano, Fernando
Romero, Alfonso
Matarraz, Sergio
Bossche, Wouter B. L.van den
Flores-Montero, Juan
Durie, B.
Dongen, J. J. M. van
Orfao, Alberto
author_role author
author2 Almeida, Julia
Teodosio, Cristina
Sanoja-Flores, Luzalba
Mayado, Andrea
Pérez-Pons, Alba
Puig, Noemi
Arana, Paula
Paiva, Bruno
Solano, Fernando
Romero, Alfonso
Matarraz, Sergio
Bossche, Wouter B. L.van den
Flores-Montero, Juan
Durie, B.
Dongen, J. J. M. van
Orfao, Alberto
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Centro de Investigación Biomédica en Red Cáncer (España)
Instituto de Salud Carlos III
European Commission
Ministerio de Economía y Competitividad (España)
European Research Council
European Commission
International Myeloma Foundation
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Plasma cell neoplasms
MGUS
Multiple myeloma
Monocytes
FcεRI monocytes
Tumor microenvironment
Inflammatory cytokines
Immunosenescence
Bone markers
topic Plasma cell neoplasms
MGUS
Multiple myeloma
Monocytes
FcεRI monocytes
Tumor microenvironment
Inflammatory cytokines
Immunosenescence
Bone markers
description © 2021 by the authors.
publishDate 2021
dc.date.none.fl_str_mv 2021
2022
2022
2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/261847
url http://hdl.handle.net/10261/261847
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/EC/H2020/695655
http://dx.doi.org/10.3390/cancers13061454
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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