Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson’s Disease
Objective To determine possible associations of hemispheric-regional alpha/theta ratio (α/θ) with neuropsychological test performance in Parkinson’s Disease (PD) non-demented patients. Methods 36 PD were matched to 36 Healthy Controls (HC). The α/θ in eight hemispheric regions was computed from the...
| Autores: | , , , , , , , , , , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Universidad de Navarra |
| Repositorio: | Dadun. Depósito Académico Digital de la Universidad de Navarra |
| Idioma: | inglés |
| OAI Identifier: | oai:dadun.unav.edu:10171/122831 |
| Acceso en línea: | https://hdl.handle.net/10171/122831 |
| Access Level: | acceso abierto |
| Palabra clave: | Electroencephalography Parkinson’s Disease Alpha rhythm Theta rhythm Neuropsychological tests |
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Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson’s DiseaseJaramillo-Jimenez, A. (Alberto)|||/items/501d62e2-1edc-44ea-b586-ad533b8a3879Suarez-Revelo, J.X. (Jazmin Ximena)|||/items/e9159510-9153-4d37-ac9d-bc264a35a0e8Ochoa-Gomez, J.F. (John Fredy)|||/items/54908892-e386-4564-a26c-7aef37603631Carmona Arroyave, J.A. (Jairo Alexander)|||/items/09477b0c-a73d-4532-87d0-7cc18018e04fBocanegra, Y. (Yamile)|||/items/3d55b45e-dfdd-4497-b5b0-fa25cfb18c29Lopera, F. (Francisco)|||/items/9b628a02-8fe7-4cce-abc3-9861832dd0b9Buritica, O. (Omar)|||/items/21a4493d-a99e-4208-ae10-a15c68d1cbadPineda-Salazar, D.A. (David Antonio)|||/items/f2d0a97e-849f-4fba-bec7-2fb4801f01bdMoreno-Gomez, L. (Leonardo)|||/items/d21ce35c-432b-46f2-9cf3-29aeecb85711Tobon-Quintero, C.A. (Carlos Andres)|||/items/2e140374-4c93-4949-93e9-9a3916005f67Borda-Borda, M.G. (Miguel German)|||/items/681ecdf1-0f23-4003-a702-417198fd228dBonanni, L. (Laura)|||/items/ba9f2f43-542c-4500-98a6-895b954f245aFfytche, D.H. (Dominic H.)|||/items/a0aa4bad-7cab-4971-bec1-d0a030c919f9Bronnick, K. (Kolbjorn)|||/items/e1cd8b45-4824-4efd-9500-de85f9cd03c4Aarsland, D. (Dag)|||/items/7f4024e7-2d11-43cf-8b41-29752ddf75e1ElectroencephalographyParkinson’s DiseaseAlpha rhythmTheta rhythmNeuropsychological testsObjective To determine possible associations of hemispheric-regional alpha/theta ratio (α/θ) with neuropsychological test performance in Parkinson’s Disease (PD) non-demented patients. Methods 36 PD were matched to 36 Healthy Controls (HC). The α/θ in eight hemispheric regions was computed from the relative power spectral density of the resting-state quantitative electroencephalogram (qEEG). Correlations between α/θ and performance in several neuropsychological tests were conducted, significant findings were included in a moderation analysis. Results The α/θ in all regions was lower in PD than in HC, with larger effect sizes in the posterior regions. Right parietal, and right and left occipital α/θ had significant positive correlations with performance in Judgement of Line Orientation Test (JLOT) in PD. Adjusted moderation analysis indicated that right, but not left, occipital α/θ influenced the JLOT performance related to PD. Conclusions Reduction of the occipital α/θ, in particular on the right side, was associated with visuospatial performance impairment in PD. Significance Visuospatial impairment in PD, which is highly correlated with the subsequent development of dementia, is reflected in α/θ in the right posterior regions. The right occipital α/θ may represent a useful qEEG marker for evaluating the presence of early signs of cognitive decline in PD and the subsequent risk of dementia.ElsevierDadun. Depósito Académico Digital Universidad de Navarra20212021-01-0120212021-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10171/122831reponame:Dadun. Depósito Académico Digital de la Universidad de Navarrainstname:Universidad de NavarraInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:dadun.unav.edu:10171/1228312026-06-21T12:47:57Z |
| dc.title.none.fl_str_mv |
Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson’s Disease |
| title |
Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson’s Disease |
| spellingShingle |
Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson’s Disease Jaramillo-Jimenez, A. (Alberto)|||/items/501d62e2-1edc-44ea-b586-ad533b8a3879 Electroencephalography Parkinson’s Disease Alpha rhythm Theta rhythm Neuropsychological tests |
| title_short |
Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson’s Disease |
| title_full |
Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson’s Disease |
| title_fullStr |
Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson’s Disease |
| title_full_unstemmed |
Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson’s Disease |
| title_sort |
Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson’s Disease |
| dc.creator.none.fl_str_mv |
Jaramillo-Jimenez, A. (Alberto)|||/items/501d62e2-1edc-44ea-b586-ad533b8a3879 Suarez-Revelo, J.X. (Jazmin Ximena)|||/items/e9159510-9153-4d37-ac9d-bc264a35a0e8 Ochoa-Gomez, J.F. (John Fredy)|||/items/54908892-e386-4564-a26c-7aef37603631 Carmona Arroyave, J.A. (Jairo Alexander)|||/items/09477b0c-a73d-4532-87d0-7cc18018e04f Bocanegra, Y. (Yamile)|||/items/3d55b45e-dfdd-4497-b5b0-fa25cfb18c29 Lopera, F. (Francisco)|||/items/9b628a02-8fe7-4cce-abc3-9861832dd0b9 Buritica, O. (Omar)|||/items/21a4493d-a99e-4208-ae10-a15c68d1cbad Pineda-Salazar, D.A. (David Antonio)|||/items/f2d0a97e-849f-4fba-bec7-2fb4801f01bd Moreno-Gomez, L. (Leonardo)|||/items/d21ce35c-432b-46f2-9cf3-29aeecb85711 Tobon-Quintero, C.A. (Carlos Andres)|||/items/2e140374-4c93-4949-93e9-9a3916005f67 Borda-Borda, M.G. (Miguel German)|||/items/681ecdf1-0f23-4003-a702-417198fd228d Bonanni, L. (Laura)|||/items/ba9f2f43-542c-4500-98a6-895b954f245a Ffytche, D.H. (Dominic H.)|||/items/a0aa4bad-7cab-4971-bec1-d0a030c919f9 Bronnick, K. (Kolbjorn)|||/items/e1cd8b45-4824-4efd-9500-de85f9cd03c4 Aarsland, D. (Dag)|||/items/7f4024e7-2d11-43cf-8b41-29752ddf75e1 |
| author |
Jaramillo-Jimenez, A. (Alberto)|||/items/501d62e2-1edc-44ea-b586-ad533b8a3879 |
| author_facet |
Jaramillo-Jimenez, A. (Alberto)|||/items/501d62e2-1edc-44ea-b586-ad533b8a3879 Suarez-Revelo, J.X. (Jazmin Ximena)|||/items/e9159510-9153-4d37-ac9d-bc264a35a0e8 Ochoa-Gomez, J.F. (John Fredy)|||/items/54908892-e386-4564-a26c-7aef37603631 Carmona Arroyave, J.A. (Jairo Alexander)|||/items/09477b0c-a73d-4532-87d0-7cc18018e04f Bocanegra, Y. (Yamile)|||/items/3d55b45e-dfdd-4497-b5b0-fa25cfb18c29 Lopera, F. (Francisco)|||/items/9b628a02-8fe7-4cce-abc3-9861832dd0b9 Buritica, O. (Omar)|||/items/21a4493d-a99e-4208-ae10-a15c68d1cbad Pineda-Salazar, D.A. (David Antonio)|||/items/f2d0a97e-849f-4fba-bec7-2fb4801f01bd Moreno-Gomez, L. (Leonardo)|||/items/d21ce35c-432b-46f2-9cf3-29aeecb85711 Tobon-Quintero, C.A. (Carlos Andres)|||/items/2e140374-4c93-4949-93e9-9a3916005f67 Borda-Borda, M.G. (Miguel German)|||/items/681ecdf1-0f23-4003-a702-417198fd228d Bonanni, L. (Laura)|||/items/ba9f2f43-542c-4500-98a6-895b954f245a Ffytche, D.H. (Dominic H.)|||/items/a0aa4bad-7cab-4971-bec1-d0a030c919f9 Bronnick, K. (Kolbjorn)|||/items/e1cd8b45-4824-4efd-9500-de85f9cd03c4 Aarsland, D. (Dag)|||/items/7f4024e7-2d11-43cf-8b41-29752ddf75e1 |
| author_role |
author |
| author2 |
Suarez-Revelo, J.X. (Jazmin Ximena)|||/items/e9159510-9153-4d37-ac9d-bc264a35a0e8 Ochoa-Gomez, J.F. (John Fredy)|||/items/54908892-e386-4564-a26c-7aef37603631 Carmona Arroyave, J.A. (Jairo Alexander)|||/items/09477b0c-a73d-4532-87d0-7cc18018e04f Bocanegra, Y. (Yamile)|||/items/3d55b45e-dfdd-4497-b5b0-fa25cfb18c29 Lopera, F. (Francisco)|||/items/9b628a02-8fe7-4cce-abc3-9861832dd0b9 Buritica, O. (Omar)|||/items/21a4493d-a99e-4208-ae10-a15c68d1cbad Pineda-Salazar, D.A. (David Antonio)|||/items/f2d0a97e-849f-4fba-bec7-2fb4801f01bd Moreno-Gomez, L. (Leonardo)|||/items/d21ce35c-432b-46f2-9cf3-29aeecb85711 Tobon-Quintero, C.A. (Carlos Andres)|||/items/2e140374-4c93-4949-93e9-9a3916005f67 Borda-Borda, M.G. (Miguel German)|||/items/681ecdf1-0f23-4003-a702-417198fd228d Bonanni, L. (Laura)|||/items/ba9f2f43-542c-4500-98a6-895b954f245a Ffytche, D.H. (Dominic H.)|||/items/a0aa4bad-7cab-4971-bec1-d0a030c919f9 Bronnick, K. (Kolbjorn)|||/items/e1cd8b45-4824-4efd-9500-de85f9cd03c4 Aarsland, D. (Dag)|||/items/7f4024e7-2d11-43cf-8b41-29752ddf75e1 |
| author2_role |
author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Dadun. Depósito Académico Digital Universidad de Navarra |
| dc.subject.none.fl_str_mv |
Electroencephalography Parkinson’s Disease Alpha rhythm Theta rhythm Neuropsychological tests |
| topic |
Electroencephalography Parkinson’s Disease Alpha rhythm Theta rhythm Neuropsychological tests |
| description |
Objective To determine possible associations of hemispheric-regional alpha/theta ratio (α/θ) with neuropsychological test performance in Parkinson’s Disease (PD) non-demented patients. Methods 36 PD were matched to 36 Healthy Controls (HC). The α/θ in eight hemispheric regions was computed from the relative power spectral density of the resting-state quantitative electroencephalogram (qEEG). Correlations between α/θ and performance in several neuropsychological tests were conducted, significant findings were included in a moderation analysis. Results The α/θ in all regions was lower in PD than in HC, with larger effect sizes in the posterior regions. Right parietal, and right and left occipital α/θ had significant positive correlations with performance in Judgement of Line Orientation Test (JLOT) in PD. Adjusted moderation analysis indicated that right, but not left, occipital α/θ influenced the JLOT performance related to PD. Conclusions Reduction of the occipital α/θ, in particular on the right side, was associated with visuospatial performance impairment in PD. Significance Visuospatial impairment in PD, which is highly correlated with the subsequent development of dementia, is reflected in α/θ in the right posterior regions. The right occipital α/θ may represent a useful qEEG marker for evaluating the presence of early signs of cognitive decline in PD and the subsequent risk of dementia. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021 2021-01-01 2021 2021-01-01 |
| dc.type.none.fl_str_mv |
journal article http://purl.org/coar/resource_type/c_6501 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.none.fl_str_mv |
https://hdl.handle.net/10171/122831 |
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https://hdl.handle.net/10171/122831 |
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Inglés eng |
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Inglés |
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eng |
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open access http://purl.org/coar/access_right/c_abf2 |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 |
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openAccess |
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application/pdf |
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Elsevier |
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Elsevier |
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reponame:Dadun. Depósito Académico Digital de la Universidad de Navarra instname:Universidad de Navarra |
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Universidad de Navarra |
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Dadun. Depósito Académico Digital de la Universidad de Navarra |
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Dadun. Depósito Académico Digital de la Universidad de Navarra |
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