Underdosing of Surfactant for Preterm Babies with Respiratory Distress Syndrome in Clinical Practice
Objective: To evaluate the initial doses of surfactant administered to preterm infants with respiratory distress syndrome. Study Design: This is a retrospective cohort study of 206 preterm infants admitted in four level III neonatal intensive care units of acute tertiary care hospitals in Spain betw...
| Autores: | , , , , , , , , , , |
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| Tipo de recurso: | informe técnico |
| Fecha de publicación: | 2019 |
| País: | España |
| Institución: | Universitat Autònoma de Barcelona |
| Repositorio: | Dipòsit Digital de Documents de la UAB |
| Idioma: | inglés |
| OAI Identifier: | oai:ddd.uab.cat:223584 |
| Acceso en línea: | https://ddd.uab.cat/record/223584 https://dx.doi.org/urn:doi:10.1055/s-0038-1675645 |
| Access Level: | acceso abierto |
| Palabra clave: | Dosage Preterm babies Respiratory distress syndrome Surfactant |
| Sumario: | Objective: To evaluate the initial doses of surfactant administered to preterm infants with respiratory distress syndrome. Study Design: This is a retrospective cohort study of 206 preterm infants admitted in four level III neonatal intensive care units of acute tertiary care hospitals in Spain between 2013 and 2015. Results: The mean initial dose of surfactant was 173.9 (37.3) mg/kg, and 47.5% of infants received a dose of 200 mg/kg ± 10% (180-220 mg/kg), 47% less than 180 mg/kg (-10%), and 5.4% more than 220 mg/kg (+10%). Very preterm infants (<28 weeks) received higher initial doses than more mature infants, but in all cases, the mean doses were below the recommended 200 mg/kg (by 9.2% in gestational age 23-28 weeks, by 15.9% in 29-32 weeks, and by 24.3% in. |
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