A probabilistic approach to compare the risk associated with heavy metals and bromine in honey from Dominican Republic, Mexico, Mozambique and Spain

[EN] This study aims to analyse the risk to consumers given the presence of heavy metals and bromine in honey from different countries. A probabilistic approach was applied to assess carcinogenic risk. Concerning exposure, Al in Spain (3.3E-04 mg/kgBw/day), B in Dominican Republic and Mexico (2E-04...

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Autores: Doménech Antich, Eva Mª|||0000-0003-3560-6355, Escriche Roberto, Mª Isabel|||0000-0003-0180-0360, Simó-Alfonso, E.A., Barragán-Huertac, B.E.
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/220613
Acceso en línea:https://riunet.upv.es/handle/10251/220613
Access Level:acceso abierto
Palabra clave:Risk assessment
Exposure
Honey
Risk characterisation
Genotoxicity
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spelling A probabilistic approach to compare the risk associated with heavy metals and bromine in honey from Dominican Republic, Mexico, Mozambique and SpainDoménech Antich, Eva Mª|||0000-0003-3560-6355Escriche Roberto, Mª Isabel|||0000-0003-0180-0360Simó-Alfonso, E.A.Barragán-Huertac, B.E.Risk assessmentExposureHoneyRisk characterisationGenotoxicity[EN] This study aims to analyse the risk to consumers given the presence of heavy metals and bromine in honey from different countries. A probabilistic approach was applied to assess carcinogenic risk. Concerning exposure, Al in Spain (3.3E-04 mg/kgBw/day), B in Dominican Republic and Mexico (2E-04 mg/kgBw/day in both cases) and Fe in Mexico and Mozambique had the highest values (5E-05 and 4.8E-05 mg/kgBw/day). In risk characterisation, the values were less than 1 for hazard index (HI), meaning that the consumption of honey represents a low level of concern for non-genotoxic effects. A combination of margin of exposure and probability of exceedance results that exposure to Pb pose no threat. The probability of suffering cancer for Br, Cd, Ni and Pb was lower than 1.0E-06 and, therefore, considered safe. However, the risk at the 95th percentile of Br in Dominican Republic was 1.18E-04 in adults and 2.45E-04 in children, exceeding 1.0E-04, and therefore, considered intolerable. Finally, the sensitivity analysis indicated that the most influential factor in the HI was the consumption in adults and the concentration of Ni in children, whereas for cancer risk, were the concentrations of Ni, Cd, Br and Pb, in both cases.This work has been funded by the ADSIDEO 2020 programme of the Centre for Development Cooperation of the Universitat Politecnica de Valencia through the project entitled: Risk Analysis of bee products in Mozambique. Social and Economic Opportunity of rural populations . This work has been also part of the project AGROALNEXT/2022/043, funded by the Next Generation European Union and the Plan de Recuperación, Transformación y Resiliencia of the Spanish Government, with the support of Generalitat Valenciana.ElsevierDepartamento de Tecnología de AlimentosInstituto Universitario de Ingeniería de Alimentos (FoodUPV)Escuela Técnica Superior de Ingeniería Agronómica y del Medio NaturalGENERALITAT VALENCIANAUNIVERSIDAD POLITECNICA DE VALENCIARepositorio Institucional de la Universitat Politècnica de València Riunet20242024-01-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfapplication/pdfhttps://riunet.upv.es/handle/10251/220613reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valénciainstname:Universitat Politècnica de València (UPV)InglésengGeneralitat Valenciana https://doi.org/10.13039/501100003359 AGROALNEXT%2F2022%2F043 TECNICAS ANALÍTICAS RÁPIDAS PARA EVALUAR SEGURIDAD, ADULTERACION Y TRAZABILIDAD EN PRODUCTOS DE LA COLMENA. APLICACIÓN A UN CULTIVO EN TRANSICIÓN AGROECOLÓGICAUniversitat Politècnica de València https://doi.org/10.13039/501100004233 AD2003 Análisis de Riesgos en productos apícolas de Mozambique. Oportunidad Social y Económica de las poblaciones ruralesopen accesshttp://purl.org/coar/access_right/c_abf2Reconocimiento - No comercial - Sin obra derivada (by-nc-nd) http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:riunet.upv.es:10251/2206132026-06-13T07:49:27Z
dc.title.none.fl_str_mv A probabilistic approach to compare the risk associated with heavy metals and bromine in honey from Dominican Republic, Mexico, Mozambique and Spain
title A probabilistic approach to compare the risk associated with heavy metals and bromine in honey from Dominican Republic, Mexico, Mozambique and Spain
spellingShingle A probabilistic approach to compare the risk associated with heavy metals and bromine in honey from Dominican Republic, Mexico, Mozambique and Spain
Doménech Antich, Eva Mª|||0000-0003-3560-6355
Risk assessment
Exposure
Honey
Risk characterisation
Genotoxicity
title_short A probabilistic approach to compare the risk associated with heavy metals and bromine in honey from Dominican Republic, Mexico, Mozambique and Spain
title_full A probabilistic approach to compare the risk associated with heavy metals and bromine in honey from Dominican Republic, Mexico, Mozambique and Spain
title_fullStr A probabilistic approach to compare the risk associated with heavy metals and bromine in honey from Dominican Republic, Mexico, Mozambique and Spain
title_full_unstemmed A probabilistic approach to compare the risk associated with heavy metals and bromine in honey from Dominican Republic, Mexico, Mozambique and Spain
title_sort A probabilistic approach to compare the risk associated with heavy metals and bromine in honey from Dominican Republic, Mexico, Mozambique and Spain
dc.creator.none.fl_str_mv Doménech Antich, Eva Mª|||0000-0003-3560-6355
Escriche Roberto, Mª Isabel|||0000-0003-0180-0360
Simó-Alfonso, E.A.
Barragán-Huertac, B.E.
author Doménech Antich, Eva Mª|||0000-0003-3560-6355
author_facet Doménech Antich, Eva Mª|||0000-0003-3560-6355
Escriche Roberto, Mª Isabel|||0000-0003-0180-0360
Simó-Alfonso, E.A.
Barragán-Huertac, B.E.
author_role author
author2 Escriche Roberto, Mª Isabel|||0000-0003-0180-0360
Simó-Alfonso, E.A.
Barragán-Huertac, B.E.
author2_role author
author
author
dc.contributor.none.fl_str_mv Departamento de Tecnología de Alimentos
Instituto Universitario de Ingeniería de Alimentos (FoodUPV)
Escuela Técnica Superior de Ingeniería Agronómica y del Medio Natural
GENERALITAT VALENCIANA
UNIVERSIDAD POLITECNICA DE VALENCIA
Repositorio Institucional de la Universitat Politècnica de València Riunet
dc.subject.none.fl_str_mv Risk assessment
Exposure
Honey
Risk characterisation
Genotoxicity
topic Risk assessment
Exposure
Honey
Risk characterisation
Genotoxicity
description [EN] This study aims to analyse the risk to consumers given the presence of heavy metals and bromine in honey from different countries. A probabilistic approach was applied to assess carcinogenic risk. Concerning exposure, Al in Spain (3.3E-04 mg/kgBw/day), B in Dominican Republic and Mexico (2E-04 mg/kgBw/day in both cases) and Fe in Mexico and Mozambique had the highest values (5E-05 and 4.8E-05 mg/kgBw/day). In risk characterisation, the values were less than 1 for hazard index (HI), meaning that the consumption of honey represents a low level of concern for non-genotoxic effects. A combination of margin of exposure and probability of exceedance results that exposure to Pb pose no threat. The probability of suffering cancer for Br, Cd, Ni and Pb was lower than 1.0E-06 and, therefore, considered safe. However, the risk at the 95th percentile of Br in Dominican Republic was 1.18E-04 in adults and 2.45E-04 in children, exceeding 1.0E-04, and therefore, considered intolerable. Finally, the sensitivity analysis indicated that the most influential factor in the HI was the consumption in adults and the concentration of Ni in children, whereas for cancer risk, were the concentrations of Ni, Cd, Br and Pb, in both cases.
publishDate 2024
dc.date.none.fl_str_mv 2024
2024-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://riunet.upv.es/handle/10251/220613
url https://riunet.upv.es/handle/10251/220613
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Generalitat Valenciana https://doi.org/10.13039/501100003359 AGROALNEXT%2F2022%2F043 TECNICAS ANALÍTICAS RÁPIDAS PARA EVALUAR SEGURIDAD, ADULTERACION Y TRAZABILIDAD EN PRODUCTOS DE LA COLMENA. APLICACIÓN A UN CULTIVO EN TRANSICIÓN AGROECOLÓGICA
Universitat Politècnica de València https://doi.org/10.13039/501100004233 AD2003 Análisis de Riesgos en productos apícolas de Mozambique. Oportunidad Social y Económica de las poblaciones rurales
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reconocimiento - No comercial - Sin obra derivada (by-nc-nd)
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reconocimiento - No comercial - Sin obra derivada (by-nc-nd)
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname:Universitat Politècnica de València (UPV)
instname_str Universitat Politècnica de València (UPV)
reponame_str RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
collection RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
repository.name.fl_str_mv
repository.mail.fl_str_mv
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