Iron hydride radical reductive alkylation of unactivated alkenes

Iron-catalyzed hydrogen atom transfer-mediated intermolecular C−C coupling reactions between alkenes and tosylhydrazones, followed by in situ cleavage of the tosylhydrazine intermediates using Et3N, are described. The process involves a new strategic bond disconnection resulting in the reductive alk...

Descripción completa

Detalles Bibliográficos
Autores: Saladrigas, Mar, Bonjoch i Sesé, Josep, Bradshaw, Ben
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2019
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/159735
Acceso en línea:https://hdl.handle.net/2445/159735
Access Level:acceso abierto
Palabra clave:Alquens
Hidrogen
Alkenes
Hydrogen
id ES_0171eca776e70cdffd313b254e66da60
oai_identifier_str oai:recercat.cat:2445/159735
network_acronym_str ES
network_name_str España
repository_id_str
spelling Iron hydride radical reductive alkylation of unactivated alkenesSaladrigas, MarBonjoch i Sesé, JosepBradshaw, BenAlquensHidrogenAlkenesHydrogenIron-catalyzed hydrogen atom transfer-mediated intermolecular C−C coupling reactions between alkenes and tosylhydrazones, followed by in situ cleavage of the tosylhydrazine intermediates using Et3N, are described. The process involves a new strategic bond disconnection resulting in the reductive alkylation of nonactivated alkenes. The reaction is operationally simple, proceeds under mild conditions, and has a wide substrate scope.American Chemical Society2020202020192020info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersion5 p.application/pdfhttps://hdl.handle.net/2445/159735Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésVersió postprint del document publicat a: https://doi.org/10.1021/acs.orglett.9b04459Organic Letters, 2019, vol. 22, num. 2, p. 684-688https://doi.org/10.1021/acs.orglett.9b04459(c) American Chemical Society , 2019info:eu-repo/semantics/openAccessoai:recercat.cat:2445/1597352026-05-29T05:05:01Z
dc.title.none.fl_str_mv Iron hydride radical reductive alkylation of unactivated alkenes
title Iron hydride radical reductive alkylation of unactivated alkenes
spellingShingle Iron hydride radical reductive alkylation of unactivated alkenes
Saladrigas, Mar
Alquens
Hidrogen
Alkenes
Hydrogen
title_short Iron hydride radical reductive alkylation of unactivated alkenes
title_full Iron hydride radical reductive alkylation of unactivated alkenes
title_fullStr Iron hydride radical reductive alkylation of unactivated alkenes
title_full_unstemmed Iron hydride radical reductive alkylation of unactivated alkenes
title_sort Iron hydride radical reductive alkylation of unactivated alkenes
dc.creator.none.fl_str_mv Saladrigas, Mar
Bonjoch i Sesé, Josep
Bradshaw, Ben
author Saladrigas, Mar
author_facet Saladrigas, Mar
Bonjoch i Sesé, Josep
Bradshaw, Ben
author_role author
author2 Bonjoch i Sesé, Josep
Bradshaw, Ben
author2_role author
author
dc.subject.none.fl_str_mv Alquens
Hidrogen
Alkenes
Hydrogen
topic Alquens
Hidrogen
Alkenes
Hydrogen
description Iron-catalyzed hydrogen atom transfer-mediated intermolecular C−C coupling reactions between alkenes and tosylhydrazones, followed by in situ cleavage of the tosylhydrazine intermediates using Et3N, are described. The process involves a new strategic bond disconnection resulting in the reductive alkylation of nonactivated alkenes. The reaction is operationally simple, proceeds under mild conditions, and has a wide substrate scope.
publishDate 2019
dc.date.none.fl_str_mv 2019
2020
2020
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/159735
url https://hdl.handle.net/2445/159735
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: https://doi.org/10.1021/acs.orglett.9b04459
Organic Letters, 2019, vol. 22, num. 2, p. 684-688
https://doi.org/10.1021/acs.orglett.9b04459
dc.rights.none.fl_str_mv (c) American Chemical Society , 2019
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) American Chemical Society , 2019
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 5 p.
application/pdf
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869402584036409344
score 15,811543

Similares en LA Referencia