Review about graphene- based biosensors for detection of SARS-COV-2

Due to the health emergency produced by SARS-CoV-2, which has generated a pandemic, this work proposes a review on developed methods for the detection of Covid-19 based on graphene biosensors, considering their physicochemical properties. This research includes a compilation and analysis of informat...

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Detalles Bibliográficos
Autores: Mena-Lizano, Daniel, Acurio, Eliana, Pachacama-Choca, Richard, Tubón-Usca, Gabriela
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Ecuador
Institución:Universidad Central del Ecuador
Repositorio:Revista FIGEMPA: Investigación y Desarrollo
Idioma:español
OAI Identifier:oai:revistadigital.uce.edu.ec:article/3519
Acceso en línea:https://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519
Access Level:acceso abierto
Palabra clave:Biosensores
covid-19
detección
grafeno
SARS-COV-2
Biosensors
detection
graphene
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spelling Review about graphene- based biosensors for detection of SARS-COV-2Revisión acerca de biosensores basados en grafeno para la detección del SARSCOV- 2.Mena-Lizano, DanielAcurio, ElianaPachacama-Choca, RichardTubón-Usca, GabrielaBiosensorescovid-19deteccióngrafenoSARS-COV-2Biosensorscovid-19detectiongrapheneSARS-COV-2Due to the health emergency produced by SARS-CoV-2, which has generated a pandemic, this work proposes a review on developed methods for the detection of Covid-19 based on graphene biosensors, considering their physicochemical properties. This research includes a compilation and analysis of information on this type of biosensors published in high-impact journals in recent years. For the development of the study, parameters such as detection time, detection limit, type of sensor, proteins that the biosensor detects, type of graphene, and cost were chosen to verify its effectiveness. The analyzed results demonstrate that most biosensors functionalizing the antibody of S, N protein or recombination of both, and some biosensors allow the detection of up to 4 types of proteins (C-reactive protein, IgG, IgM, and nucleapside). Several of the analyzed studies show a specific sequence detection of the virus and a low limit of detection (LOD) ranging from 0.1 fg/mL to 1 fg/mL, which allows detecting SARS-CoV-2 at low concentrations. In conclusion, the analysis indicates a feasible option for the implementation of graphene-based biosensors as an alternative to traditional test.Debido a la emergencia sanitaria producida por el SARS-CoV-2 que ha generado una pandemia, en este trabajo se propone una revisión sobre métodos desarrollados para la detección de Covid-19 basados en biosensores de grafeno, considerando sus propiedades fisicoquímicas. Esta investigación abarca una recopilación y análisis de información sobre biosensores en revistas de alto impacto en los últimos dos años. Para el desarrollo del estudio, se escogieron parámetros como: tiempo de detección, límite de detección, tipo de sensor, proteínas que detecta el biosensor, tipo de grafeno y costo, a fin de comprobar su efectividad. Los resultados analizados demuestran que la mayoría de biosensores funcionalizan el anticuerpo de la proteína S, N o una recombinación de ambas, y, algunos biosensores permiten la detección de hasta 4 tipos de proteínas (proteína reactiva C, IgG, IgM y nucleapside). Varios de los estudios analizados muestran una detección de secuencia especifica del virus y un bajo límite de detección (LOD) que va desde 0,1 fg/mL hasta a 1 fg/mL, lo que permite detectar SARS-CoV-2 a bajas concentraciones. El análisis indica una opción factible para la implementación de biosensores basados en grafeno como alternativa a las pruebas tradicionales.Facultad de Ingeniería en Geología, Minas, Petróleos y Ambiental - Universidad Central del Ecuador2021-12-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/xmlapplication/ziphttps://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/351910.29166/revfig.v12i2.3519FIGEMPA: Investigación y Desarrollo; Vol. 12 No. 2 (2021): Rediscover; 70-84FIGEMPA: Investigación y Desarrollo; Vol. 12 Núm. 2 (2021): Reencuentro; 70-842602-84841390-704210.29166/revfig.v12i2reponame:Revista FIGEMPA: Investigación y Desarrolloinstname:Universidad Central del Ecuadorinstacron:UCEspahttps://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519/4305https://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519/4348https://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519/4349Derechos de autor 2021 Daniel Mena-Lizano, Eliana Acurio, Richard Pachacama-Choca, Gabriela Tubón-Uscahttp://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccess2021-12-21T17:39:39Zoai:revistadigital.uce.edu.ec:article/3519Portal de revistashttps://revistadigital.uce.edu.ec/Universidad públicahttps://uce.edu.ec/**Ecuador*602-84841390-7042opendoar:02021-12-21T17:39:39Revista FIGEMPA: Investigación y Desarrollo - Universidad Central del Ecuadorfalse
dc.title.none.fl_str_mv Review about graphene- based biosensors for detection of SARS-COV-2
Revisión acerca de biosensores basados en grafeno para la detección del SARSCOV- 2.
title Review about graphene- based biosensors for detection of SARS-COV-2
spellingShingle Review about graphene- based biosensors for detection of SARS-COV-2
Mena-Lizano, Daniel
Biosensores
covid-19
detección
grafeno
SARS-COV-2
Biosensors
covid-19
detection
graphene
SARS-COV-2
title_short Review about graphene- based biosensors for detection of SARS-COV-2
title_full Review about graphene- based biosensors for detection of SARS-COV-2
title_fullStr Review about graphene- based biosensors for detection of SARS-COV-2
title_full_unstemmed Review about graphene- based biosensors for detection of SARS-COV-2
title_sort Review about graphene- based biosensors for detection of SARS-COV-2
dc.creator.none.fl_str_mv Mena-Lizano, Daniel
Acurio, Eliana
Pachacama-Choca, Richard
Tubón-Usca, Gabriela
author Mena-Lizano, Daniel
author_facet Mena-Lizano, Daniel
Acurio, Eliana
Pachacama-Choca, Richard
Tubón-Usca, Gabriela
author_role author
author2 Acurio, Eliana
Pachacama-Choca, Richard
Tubón-Usca, Gabriela
author2_role author
author
author
dc.subject.none.fl_str_mv Biosensores
covid-19
detección
grafeno
SARS-COV-2
Biosensors
covid-19
detection
graphene
SARS-COV-2
topic Biosensores
covid-19
detección
grafeno
SARS-COV-2
Biosensors
covid-19
detection
graphene
SARS-COV-2
description Due to the health emergency produced by SARS-CoV-2, which has generated a pandemic, this work proposes a review on developed methods for the detection of Covid-19 based on graphene biosensors, considering their physicochemical properties. This research includes a compilation and analysis of information on this type of biosensors published in high-impact journals in recent years. For the development of the study, parameters such as detection time, detection limit, type of sensor, proteins that the biosensor detects, type of graphene, and cost were chosen to verify its effectiveness. The analyzed results demonstrate that most biosensors functionalizing the antibody of S, N protein or recombination of both, and some biosensors allow the detection of up to 4 types of proteins (C-reactive protein, IgG, IgM, and nucleapside). Several of the analyzed studies show a specific sequence detection of the virus and a low limit of detection (LOD) ranging from 0.1 fg/mL to 1 fg/mL, which allows detecting SARS-CoV-2 at low concentrations. In conclusion, the analysis indicates a feasible option for the implementation of graphene-based biosensors as an alternative to traditional test.
publishDate 2021
dc.date.none.fl_str_mv 2021-12-16
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519
10.29166/revfig.v12i2.3519
url https://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519
identifier_str_mv 10.29166/revfig.v12i2.3519
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519/4305
https://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519/4348
https://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519/4349
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
text/xml
application/zip
dc.publisher.none.fl_str_mv Facultad de Ingeniería en Geología, Minas, Petróleos y Ambiental - Universidad Central del Ecuador
publisher.none.fl_str_mv Facultad de Ingeniería en Geología, Minas, Petróleos y Ambiental - Universidad Central del Ecuador
dc.source.none.fl_str_mv FIGEMPA: Investigación y Desarrollo; Vol. 12 No. 2 (2021): Rediscover; 70-84
FIGEMPA: Investigación y Desarrollo; Vol. 12 Núm. 2 (2021): Reencuentro; 70-84
2602-8484
1390-7042
10.29166/revfig.v12i2
reponame:Revista FIGEMPA: Investigación y Desarrollo
instname:Universidad Central del Ecuador
instacron:UCE
instname_str Universidad Central del Ecuador
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institution UCE
reponame_str Revista FIGEMPA: Investigación y Desarrollo
collection Revista FIGEMPA: Investigación y Desarrollo
repository.name.fl_str_mv Revista FIGEMPA: Investigación y Desarrollo - Universidad Central del Ecuador
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