Synthesis of 2-hydroxy-3-substituted naphthoquinones using the Heck reaction
An efficient Heck coupling of 2-hydroxy-3-iodo-naphthoquinone with a series of electron-deficient alkenes in aqueous solution has been accomplished. The method is characterized by simple conditions and facile work-up to isolate the products in good to excellent yields. The products contain the motif...
| Autores: | , , |
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| Tipo de documento: | artigo |
| Data de publicação: | 2007 |
| País: | Costa Rica |
| Recursos: | Universidad de Costa Rica |
| Repositório: | Kérwá |
| OAI Identifier: | oai:kerwa.ucr.ac.cr:10669/28843 |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S0040403907006922 https://hdl.handle.net/10669/28843 |
| Access Level: | Acesso embargado |
| Palavra-chave: | Heck reaction Hooker condensation Naphthoquinone 2-Hydroxy-3-iodonaphthoquinone |
| Resumo: | An efficient Heck coupling of 2-hydroxy-3-iodo-naphthoquinone with a series of electron-deficient alkenes in aqueous solution has been accomplished. The method is characterized by simple conditions and facile work-up to isolate the products in good to excellent yields. The products contain the motif present in several naphthoquinone pigments but with enhanced polarity. |
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