Amiloidosis primaria asociada a mielofibrosis idiopática crónica. Una relación inusual
Introduction: amyloidosis is the term used for diseases caused by the extracellular deposition of protein fibrils in tissues and organs. These diseases are defined and classified by the biochemical nature of the protein in the fibril deposits. Clinical case: it is presented a clinical case of a pati...
| Autores: | , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2012 |
| País: | Colombia |
| Institución: | Universidad Industrial de Santander |
| Repositorio: | Repositorio UIS |
| Idioma: | español |
| OAI Identifier: | oai:noesis.uis.edu.co:20.500.14071/5689 |
| Acceso en línea: | https://revistas.uis.edu.co/index.php/revistamedicasuis/article/view/3152 https://noesis.uis.edu.co/handle/20.500.14071/5689 |
| Access Level: | acceso abierto |
| Palabra clave: | Primary Amyloidosis Myelofibrosis Extramedullary Hematopoiesis Amiloidosis Mielofibrosis Hematopoyesis Extramedular |
| Sumario: | Introduction: amyloidosis is the term used for diseases caused by the extracellular deposition of protein fibrils in tissues and organs. These diseases are defined and classified by the biochemical nature of the protein in the fibril deposits. Clinical case: it is presented a clinical case of a patient with the diagnosis of primary amyloidosis and chronic idiopathic myelofibrosis with extramedullary hematopoiesis in the spleen. A 61-year male patient is admitted due to presenting infiltrative restrictive cardiomyopathy, hematologic alterations, hepatosplenomegalia and sensorimotor neuropathy. Amyloidosis is diagnosed through bone marrow biopsy, while fine-needle aspiration cytology of the spleen demonstrates extramedullary hematopoiesis, and along with hematologic studies, it is concluded as a chronicidiopathic myelofibrosis. Conclusions: in Universitary Hospital, imaging and histological studies are important to confirm the diagnosis of amyloidosis. The causality between primary amyloidosis and chronic idiopathic myelofibrosis there has not been reported in the literature. (MÉD.UIS. 2012;25(2):137-44) |
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