Nox inhibition improves beta-adrenergic stimulated contractility and intracellular calcium handling in the aged rat heart

Cardiac aging is characterized by alterations in contractility and intracellular calcium ([Ca2+](i)) homeostasis. It has been suggested that oxidative stress may be involved in this process. We and others have reported that in cardiomyopathies the NADPH

Detalles Bibliográficos
Autores: Valdes, Alvaro, Treuer, Adriana V, Barrios, Guillermo, Ponce, Nikol, Fuentealba, Roberto, Dulce, Raul A, Gonzalez, Daniel R
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Chile
Idioma:inglés
OAI Identifier:oai:repositorio.anid.cl:10533/232576
Acceso en línea:https://hdl.handle.net/10533/232576
Access Level:acceso abierto
Descripción
Sumario:Cardiac aging is characterized by alterations in contractility and intracellular calcium ([Ca2+](i)) homeostasis. It has been suggested that oxidative stress may be involved in this process. We and others have reported that in cardiomyopathies the NADPH