Nitric oxide synthase 1 modulates basal and beta-adrenergic-stimulated contractility by rapid and reversible redox-dependent s-nitrosylation of the heart

S-nitrosylation of several Ca2+ regulating proteins in response to beta-adrenergic stimulation was recently described in the heart; however the specific nitric oxide synthase (NOS) isoform and signaling pathways responsible for this modification have not

Detalhes bibliográficos
Autores: Vielma, Alejandra Z, Leon, Luisa, Fernandez, Ignacio C, Gonzalez, Daniel R, Boric, Mauricio P
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2015
País:Chile
Idioma:inglês
OAI Identifier:oai:repositorio.anid.cl:10533/232575
Acesso em linha:https://hdl.handle.net/10533/232575
Access Level:Acceso aberto
Descrição
Resumo:S-nitrosylation of several Ca2+ regulating proteins in response to beta-adrenergic stimulation was recently described in the heart; however the specific nitric oxide synthase (NOS) isoform and signaling pathways responsible for this modification have not