A Feed-Forward Mechanism Involving the NOX Complex and RyR-Mediated Ca2 Release During Axonal Specification

Physiological levels of ROS support neurite outgrowth and axonal specification, but the mechanisms by which ROS are able to shape neurons remain unknown. Ca2+, a broad intracellular second messenger, promotes both Rac1 activation and neurite extension. Ca

Detalles Bibliográficos
Autores: Wilson, C., Muñoz-Palma, E., Henriquez, D. R., Palmisano, I., Nuñez, M. T., Di Giovanni, S., Gonzalez-Billault, C.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2016
País:Chile
Idioma:inglés
OAI Identifier:oai:repositorio.anid.cl:10533/240119
Acceso en línea:https://hdl.handle.net/10533/240119
Access Level:acceso abierto
Descripción
Sumario:Physiological levels of ROS support neurite outgrowth and axonal specification, but the mechanisms by which ROS are able to shape neurons remain unknown. Ca2+, a broad intracellular second messenger, promotes both Rac1 activation and neurite extension. Ca