Role of the cys loop and transmembrane domain in the allosteric modulation of alpha 4 beta 2 nicotinic acetylcholine receptors

Allosteric modulators of pentameric ligand-gated ion channels are thought to act on elements of the pathways that couple agonist binding to channel gating. Using alpha 4 beta 2 nicotinic acetylcholine receptors and the alpha 4 beta 2-selective positive mo

Bibliographic Details
Authors: Alcaino, Constanza, Musgaard, Maria, Minguez, Teresa, Mazzaferro, Simone, Faundez, Manuel, Iturriaga-Vasquez, Patricio, Biggin, Philip C, Bermudez, Isabel
Format: article
Status:Published version
Publication Date:2015
Country:Chile
Language:English
OAI Identifier:oai:repositorio.anid.cl:10533/232747
Online Access:https://hdl.handle.net/10533/232747
Access Level:Open access
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spelling Bermudez, IsabelBiggin, Philip CIturriaga-Vasquez, PatricioFaundez, ManuelMazzaferro, SimoneMinguez, TeresaMusgaard, MariaAlcaino, Constanza201710.1074/jbc.M116.751206https://hdl.handle.net/10533/232747http://purl.org/coar/access_right/c_abf2Role of the cys loop and transmembrane domain in the allosteric modulation of alpha 4 beta 2 nicotinic acetylcholine receptorsAlcaino, ConstanzaMusgaard, MariaMinguez, TeresaMazzaferro, SimoneFaundez, ManuelIturriaga-Vasquez, PatricioBiggin, Philip CBermudez, Isabel2018-12-07T13:33:48Z2022-07-07T21:40:56Z20152018-12-07T13:33:48Z2022-07-07T21:40:56Z2017Allosteric modulators of pentameric ligand-gated ion channels are thought to act on elements of the pathways that couple agonist binding to channel gating. Using alpha 4 beta 2 nicotinic acetylcholine receptors and the alpha 4 beta 2-selective positive moRegularFONDECYTFONDECYT11506151150615virtual::19710-1WOS:000392316100012https://hdl.handle.net/10533/232747enghandle/10533/11155710.1074/jbc.M116.751206handle/10533/111541handle/10533/108045http://www.jbc.org/content/292/2/551.fullAtribución-NoComercial-SinDerivadas 3.0 Chilehttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/info:eu-repo/semantics/openAccessRole of the cys loop and transmembrane domain in the allosteric modulation of alpha 4 beta 2 nicotinic acetylcholine receptorsJournal Of Biological ChemistryArticuloinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttps://hdl.handle.net/10533/232747FONDECYThttp://purl.org/coar/resource_type/c_2df8fbb178c5c6a5-95d4-45ba-84ba-fb89d3deeb35virtual::19710-178c5c6a5-95d4-45ba-84ba-fb89d3deeb35virtual::19710-110533/232747oai:repositorio.anid.cl:10533/2327472023-07-24 19:54:27.334https://repositorio.anid.clRepositorio ANIDaletelier@anid.cl
dc.title.none.fl_str_mv Role of the cys loop and transmembrane domain in the allosteric modulation of alpha 4 beta 2 nicotinic acetylcholine receptors
dc.title.journal.none.fl_str_mv Journal Of Biological Chemistry
title Role of the cys loop and transmembrane domain in the allosteric modulation of alpha 4 beta 2 nicotinic acetylcholine receptors
spellingShingle Role of the cys loop and transmembrane domain in the allosteric modulation of alpha 4 beta 2 nicotinic acetylcholine receptors
Alcaino, Constanza
title_short Role of the cys loop and transmembrane domain in the allosteric modulation of alpha 4 beta 2 nicotinic acetylcholine receptors
title_full Role of the cys loop and transmembrane domain in the allosteric modulation of alpha 4 beta 2 nicotinic acetylcholine receptors
title_fullStr Role of the cys loop and transmembrane domain in the allosteric modulation of alpha 4 beta 2 nicotinic acetylcholine receptors
title_full_unstemmed Role of the cys loop and transmembrane domain in the allosteric modulation of alpha 4 beta 2 nicotinic acetylcholine receptors
title_sort Role of the cys loop and transmembrane domain in the allosteric modulation of alpha 4 beta 2 nicotinic acetylcholine receptors
dc.creator.none.fl_str_mv Alcaino, Constanza
Musgaard, Maria
Minguez, Teresa
Mazzaferro, Simone
Faundez, Manuel
Iturriaga-Vasquez, Patricio
Biggin, Philip C
Bermudez, Isabel
author Alcaino, Constanza
author_facet Alcaino, Constanza
Musgaard, Maria
Minguez, Teresa
Mazzaferro, Simone
Faundez, Manuel
Iturriaga-Vasquez, Patricio
Biggin, Philip C
Bermudez, Isabel
author_role author
author2 Musgaard, Maria
Minguez, Teresa
Mazzaferro, Simone
Faundez, Manuel
Iturriaga-Vasquez, Patricio
Biggin, Philip C
Bermudez, Isabel
author2_role author
author
author
author
author
author
author
description Allosteric modulators of pentameric ligand-gated ion channels are thought to act on elements of the pathways that couple agonist binding to channel gating. Using alpha 4 beta 2 nicotinic acetylcholine receptors and the alpha 4 beta 2-selective positive mo
publishDate 2015
dc.date.annoconcurso.none.fl_str_mv 2015
dc.date.issued.none.fl_str_mv 2017
dc.date.accessioned.none.fl_str_mv 2018-12-07T13:33:48Z
2022-07-07T21:40:56Z
dc.date.available.none.fl_str_mv 2018-12-07T13:33:48Z
2022-07-07T21:40:56Z
dc.type.none.fl_str_mv Articulo
dc.type.driver.none.fl_str_mv info:eu-repo/semantics/article
dc.type.openaire.none.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.folio.none.fl_str_mv 1150615
1150615
dc.identifier.idwos.none.fl_str_mv WOS:000392316100012
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/10533/232747
identifier_str_mv 1150615
WOS:000392316100012
url https://hdl.handle.net/10533/232747
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.contest.none.fl_str_mv handle/10533/111557
dc.relation.doi.none.fl_str_mv 10.1074/jbc.M116.751206
dc.relation.instrument.none.fl_str_mv handle/10533/111541
dc.relation.program.none.fl_str_mv handle/10533/108045
dc.relation.uri.none.fl_str_mv http://www.jbc.org/content/292/2/551.full
dc.rights.none.fl_str_mv Atribución-NoComercial-SinDerivadas 3.0 Chile
http://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.rights.driver.none.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv Atribución-NoComercial-SinDerivadas 3.0 Chile
http://creativecommons.org/licenses/by-nc-nd/3.0/cl/
eu_rights_str_mv openAccess
repository.name.fl_str_mv Repositorio ANID
repository.mail.fl_str_mv aletelier@anid.cl
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score 15.812455

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