Endoplasmic Reticulum Stress and the Hallmarks of Cancer

Tumor cells are often exposed to intrinsic and external factors that alter protein homeostasis, thus producing endoplasmic reticulum (ER) stress. To cope with this, cells evoke an adaptive mechanism to restore ER proteostasis known as the unfolded protein

Detalles Bibliográficos
Autores: Urra, H., Dufey, E., Avril, T., Chevet, E., Hetz, C.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2016
País:Chile
Idioma:inglés
OAI Identifier:oai:repositorio.anid.cl:10533/240158
Acceso en línea:https://hdl.handle.net/10533/240158
Access Level:acceso abierto
Descripción
Sumario:Tumor cells are often exposed to intrinsic and external factors that alter protein homeostasis, thus producing endoplasmic reticulum (ER) stress. To cope with this, cells evoke an adaptive mechanism to restore ER proteostasis known as the unfolded protein