Oxidative Stress and Endoplasmic Reticulum Stress in Rare Respiratory Diseases.

Several studies have shown that some rare respiratory diseases, such as alpha-1 antitrypsin deficiency (AATD), idiopathic pulmonary fibrosis (IPF), cystic fibrosis (CF), and primary ciliary dyskinesia (PCD) present oxidative stress (OS) and endoplasmic reticulum (ER) stress. Their involvement in the...

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Bibliographic Details
Authors: Magallon, M, Carrion, AE, Banuls, L, Pellicer, D, Castillo, S, Bondia, S, Navarro-Garcia, MM, Gonzalez, C, Dasi, F
Format: article
Status:Published version
Publication Date:2021
Country:España
Institution:INCLIVA
Repository:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
OAI Identifier:oai:incliva.fundanetsuite.com:p16171
Online Access:https://incliva.portalinvestigacion.com/publicaciones/16171
Access Level:Open access
Keyword:Alpha-1 antitrypsin deficiency
antioxidant therapies
cystic fibrosis
endoplasmic reticulum stress
idiopathic pulmonary fibrosis
oxidative stress
primary ciliary dyskinesia
rare respiratory diseases
Description
Summary:Several studies have shown that some rare respiratory diseases, such as alpha-1 antitrypsin deficiency (AATD), idiopathic pulmonary fibrosis (IPF), cystic fibrosis (CF), and primary ciliary dyskinesia (PCD) present oxidative stress (OS) and endoplasmic reticulum (ER) stress. Their involvement in these pathologies and the use of antioxidants as therapeutic agents to minimize the effects of OS are discussed in this review.

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