Niemann-Pick C2 Protein Expression Regulates Lithogenic Diet-Induced Gallstone Formation and Dietary Cholesterol Metabolism in Mice.

Niemann-Pick C2 protein (NPC2) is a lysosomal soluble protein that is highly expressed in the liver; it binds to cholesterol and is involved in intracellular cholesterol trafficking, allowing the exit of lysosomal cholesterol obtained via the lipoprotein

Detalhes bibliográficos
Autores: Balboa, E., Morales, G., Aylwin, P., Carrasco, G., Amigo, L., Castro, J., Rigotti, A., Zanlungo, S.
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2011
País:Chile
Idioma:inglés
OAI Identifier:oai:repositorio.anid.cl:10533/241400
Acesso em linha:https://hdl.handle.net/10533/241400
Access Level:acceso abierto
Descrição
Resumo:Niemann-Pick C2 protein (NPC2) is a lysosomal soluble protein that is highly expressed in the liver; it binds to cholesterol and is involved in intracellular cholesterol trafficking, allowing the exit of lysosomal cholesterol obtained via the lipoprotein